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Page 1
Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors.
Ouyang X, Chen X, Piatnitski EL, Kiselyov AS, He HY, Mao Y, Pattaropong V, Yu Y, Kim KH, Kincaid J, Smith L 2nd, Wong WC, Lee SP, Milligan DL, Malikzay A, Fleming J, Gerlak J, Deevi D, Doody JF, Chiang HH, Patel SN, Wang Y, Rolser RL, Kussie P, Labelle M, Tuma MC. Ouyang X, et al. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5154-9. doi: 10.1016/j.bmcl.2005.08.056. Epub 2005 Sep 28. Bioorg Med Chem Lett. 2005. PMID: 16198562
Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines.
Ouyang X, Piatnitski EL, Pattaropong V, Chen X, He HY, Kiselyov AS, Velankar A, Kawakami J, Labelle M, Smith L 2nd, Lohman J, Lee SP, Malikzay A, Fleming J, Gerlak J, Wang Y, Rosler RL, Zhou K, Mitelman S, Camara M, Surguladze D, Doody JF, Tuma MC. Ouyang X, et al. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1191-6. doi: 10.1016/j.bmcl.2005.11.094. Epub 2006 Jan 11. Bioorg Med Chem Lett. 2006. PMID: 16377187
Tricyclic azepine derivatives: pyrimido[4,5-b]-1,4-benzoxazepines as a novel class of epidermal growth factor receptor kinase inhibitors.
Smith L 2nd, Piatnitski EL, Kiselyov AS, Ouyang X, Chen X, Burdzovic-Wizemann S, Xu Y, Pan W, Chen X, Wang Y, Rosler RL, Patel SN, Chiang HH, Milligan DL, Columbus J, Wong WC, Doody JF, Hadari YR. Smith L 2nd, et al. Among authors: ouyang x. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1643-6. doi: 10.1016/j.bmcl.2005.12.018. Epub 2006 Jan 18. Bioorg Med Chem Lett. 2006. PMID: 16412636
Discovery of Dual VEGFR-2 and Tubulin Inhibitors with in Vivo Efficacy.
Chekler EL, Kiselyov AS, Ouyang X, Chen X, Pattaropong V, Wang Y, Tuma MC, Doody JF. Chekler EL, et al. Among authors: ouyang x. ACS Med Chem Lett. 2010 Aug 20;1(9):488-92. doi: 10.1021/ml1001568. eCollection 2010 Dec 9. ACS Med Chem Lett. 2010. PMID: 24900236 Free PMC article.
Antitumor Activity of IMC-038525, a Novel Oral Tubulin Polymerization Inhibitor.
Tuma MC, Malikzay A, Ouyang X, Surguladze D, Fleming J, Mitelman S, Camara M, Finnerty B, Doody J, Chekler EL, Kussie P, Tonra JR. Tuma MC, et al. Among authors: ouyang x. Transl Oncol. 2010 Oct 1;3(5):318-25. doi: 10.1593/tlo.10160. Transl Oncol. 2010. PMID: 20885894 Free PMC article.
Discovery of N-phenyl nicotinamides as potent inhibitors of Kdr.
Dominguez C, Smith L, Huang Q, Yuan C, Ouyang X, Cai L, Chen P, Kim J, Harvey T, Syed R, Kim TS, Tasker A, Wang L, Zhang M, Coxon A, Bready J, Starnes C, Chen D, Gan Y, Neervannan S, Kumar G, Polverino A, Kendall R. Dominguez C, et al. Among authors: ouyang x. Bioorg Med Chem Lett. 2007 Nov 1;17(21):6003-8. doi: 10.1016/j.bmcl.2007.07.077. Epub 2007 Aug 22. Bioorg Med Chem Lett. 2007. PMID: 17869515
1,745 results