Tsay FR - Search Results

1

An efficient synthesis of a dual PPAR alpha/gamma agonist and the formation of a sterically congested alpha-aryloxyisobutyric acid via a Bargellini reaction.

Cvetovich RJ, Chung JY, Kress MH, Amato JS, Matty L, Weingarten MD, Tsay FR, Li Z, Zhou G. Cvetovich RJ, et al. Among authors: tsay fr. J Org Chem. 2005 Oct 14;70(21):8560-3. doi: 10.1021/jo051027+. J Org Chem. 2005. PMID: 16209608

2

Highly Chemoselective Trichloroacetimidate-Mediated Alkylation of Ascomycin: A Convergent, Practical Synthesis of the Immunosuppressant L-733,725.

Song Z, DeMarco A, Zhao M, Corley EG, Thompson AS, McNamara J, Li Y, Rieger D, Sohar P, Mathre DJ, Tschaen DM, Reamer RA, Huntington MF, Ho GJ, Tsay FR, Emerson K, Shuman R, Grabowski EJ, Reider PJ. Song Z, et al. Among authors: tsay fr. J Org Chem. 1999 Mar 19;64(6):1859-1867. doi: 10.1021/jo981805g. J Org Chem. 1999. PMID: 11674275

3

Development of a new and practical route to chiral 3,4-disubstituted cyclopentanones: asymmetric alkylation and intramolecular cyclopropanation as key C-C bond-forming steps.

Palucki M, Um JM, Yasuda N, Conlon DA, Tsay FR, Hartner FW, Hsiao Y, Marcune B, Karady S, Hughes DL, Dormer PG, Reider PJ. Palucki M, et al. Among authors: tsay fr. J Org Chem. 2002 Aug 9;67(16):5508-16. doi: 10.1021/jo025890a. J Org Chem. 2002. PMID: 12153248

4

An improved preparation of 3,5-bis(trifluoromethyl)acetophenone and safety considerations in the preparation of 3,5-bis(trifluoromethyl)phenyl Grignard reagent.

Leazer JL Jr, Cvetovich R, Tsay FR, Dolling U, Vickery T, Bachert D. Leazer JL Jr, et al. Among authors: tsay fr. J Org Chem. 2003 May 2;68(9):3695-8. doi: 10.1021/jo026903n. J Org Chem. 2003. PMID: 12713381

5

Synthesis of 3-aminopyrazinone mediated by 2-pyridylthioimidate-ZnCl2 complexes. Development of an efficient route to a thrombin inhibitor.

Chung JY, Cvetovich RJ, Tsay FR, Dormer PG, DiMichele L, Mathre DJ, Chilenski JR, Mao B, Wenslow R. Chung JY, et al. Among authors: tsay fr. J Org Chem. 2003 Nov 14;68(23):8838-46. doi: 10.1021/jo034835e. J Org Chem. 2003. PMID: 14604352

6

Practical synthesis of the new carbapenem antibiotic ertapenem sodium.

Williams JM, Brands KM, Skerlj RT, Jobson RB, Marchesini G, Conrad KM, Pipik B, Savary KA, Tsay FR, Houghton PG, Sidler DR, Dolling UH, DiMichele LM, Novak TJ. Williams JM, et al. Among authors: tsay fr. J Org Chem. 2005 Sep 16;70(19):7479-87. doi: 10.1021/jo0501442. J Org Chem. 2005. PMID: 16149774

7

Stereoselective syntheses of highly functionalized bicyclo[3.1.0]hexanes: a general methodology for the synthesis of potent and selective mGluR2/3 agonists.

Tan L, Yasuda N, Yoshikawa N, Hartner FW, Eng KK, Leonard WR, Tsay FR, Volante RP, Tillyer RD. Tan L, et al. Among authors: tsay fr. J Org Chem. 2005 Sep 30;70(20):8027-34. doi: 10.1021/jo0511187. J Org Chem. 2005. PMID: 16277324

8

Synthesis of a naphthyridone p38 MAP kinase inhibitor.

Chung JY, Cvetovich RJ, McLaughlin M, Amato J, Tsay FR, Jensen M, Weissman S, Zewge D. Chung JY, et al. Among authors: tsay fr. J Org Chem. 2006 Oct 27;71(22):8602-9. doi: 10.1021/jo061618f. J Org Chem. 2006. PMID: 17064039

9

Synthesis of a Complex and Highly Potent PCSK9 Inhibitor.

Kuethe JT, Lee J, Thaisrivongs D, Yasuda N, Pollack SR, Leone J, DaSilva J, Biba M, Tsay FR, Regalado EL, Qi J, Li H, Poggetto GD, Cohen R. Kuethe JT, et al. Among authors: tsay fr. Org Lett. 2023 Jul 14;25(27):5001-5005. doi: 10.1021/acs.orglett.3c01635. Epub 2023 Jun 29. Org Lett. 2023. PMID: 37382389

10

Stereoselective synthesis of an anti-HIV drug candidate.

Conlon DA, Jensen MS, Palucki M, Yasuda N, Um JM, Yang C, Hartner FW, Tsay FR, Hsiao Y, Pye P, Rivera NR, Hughes DL. Conlon DA, et al. Among authors: tsay fr. Chirality. 2005;17 Suppl:S149-58. doi: 10.1002/chir.20137. Chirality. 2005. PMID: 15806573

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