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Genetic variations in the tissue factor gene are associated with clinical outcome in acute coronary syndrome and expression levels in human monocytes.
Mälarstig A, Tenno T, Johnston N, Lagerqvist B, Axelsson T, Syvänen AC, Wallentin L, Siegbahn A. Mälarstig A, et al. Among authors: syvanen ac. Arterioscler Thromb Vasc Biol. 2005 Dec;25(12):2667-72. doi: 10.1161/01.ATV.0000191637.48129.9b. Epub 2005 Oct 20. Arterioscler Thromb Vasc Biol. 2005. PMID: 16239598
Variants of the interferon regulatory factor 5 gene regulate expression of IRF5 mRNA in atherosclerotic tissue but are not associated with myocardial infarction.
Mälarstig A, Sigurdsson S, Eriksson P, Paulsson-Berne G, Hedin U, Wallentin L, Siegbahn A, Hamsten A, Syvänen AC. Mälarstig A, et al. Among authors: syvanen ac. Arterioscler Thromb Vasc Biol. 2008 May;28(5):975-82. doi: 10.1161/ATVBAHA.108.163733. Epub 2008 Mar 6. Arterioscler Thromb Vasc Biol. 2008. PMID: 18323517
Niemann-Pick C1 modulates hepatic triglyceride metabolism and its genetic variation contributes to serum triglyceride levels.
Uronen RL, Lundmark P, Orho-Melander M, Jauhiainen M, Larsson K, Siegbahn A, Wallentin L, Zethelius B, Melander O, Syvänen AC, Ikonen E. Uronen RL, et al. Among authors: syvanen ac. Arterioscler Thromb Vasc Biol. 2010 Aug;30(8):1614-20. doi: 10.1161/ATVBAHA.110.207191. Epub 2010 May 20. Arterioscler Thromb Vasc Biol. 2010. PMID: 20489167
Common and low-frequency genetic variants in the PCSK9 locus influence circulating PCSK9 levels.
Chernogubova E, Strawbridge R, Mahdessian H, Mälarstig A, Krapivner S, Gigante B, Hellénius ML, de Faire U, Franco-Cereceda A, Syvänen AC, Troutt JS, Konrad RJ, Eriksson P, Hamsten A, van 't Hooft FM. Chernogubova E, et al. Among authors: syvanen ac. Arterioscler Thromb Vasc Biol. 2012 Jun;32(6):1526-34. doi: 10.1161/ATVBAHA.111.240549. Epub 2012 Mar 29. Arterioscler Thromb Vasc Biol. 2012. PMID: 22460556
Effect of genetic variations on ticagrelor plasma levels and clinical outcomes.
Varenhorst C, Eriksson N, Johansson Å, Barratt BJ, Hagström E, Åkerblom A, Syvänen AC, Becker RC, James SK, Katus HA, Husted S, Steg PG, Siegbahn A, Voora D, Teng R, Storey RF, Wallentin L; PLATO Investigators. Varenhorst C, et al. Among authors: syvanen ac. Eur Heart J. 2015 Aug 1;36(29):1901-12. doi: 10.1093/eurheartj/ehv116. Epub 2015 May 2. Eur Heart J. 2015. PMID: 25935875 Clinical Trial.
Genome-wide association and Mendelian randomization study of NT-proBNP in patients with acute coronary syndrome.
Johansson Å, Eriksson N, Lindholm D, Varenhorst C, James S, Syvänen AC, Axelsson T, Siegbahn A, Barratt BJ, Becker RC, Himmelmann A, Katus HA, Steg PG, Storey RF, Wallentin L; PLATO Investigators. Johansson Å, et al. Among authors: syvanen ac. Hum Mol Genet. 2016 Apr 1;25(7):1447-56. doi: 10.1093/hmg/ddw012. Epub 2016 Jan 21. Hum Mol Genet. 2016. PMID: 26908625 Clinical Trial.
GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb.
den Hoed M, Strawbridge RJ, Almgren P, Gustafsson S, Axelsson T, Engström G, de Faire U, Hedblad B, Humphries SE, Lindgren CM, Morris AP, Östling G, Syvänen AC, Tremoli E, Hamsten A, Ingelsson E, Melander O, Lind L. den Hoed M, et al. Among authors: syvanen ac. Atherosclerosis. 2015 Apr;239(2):304-10. doi: 10.1016/j.atherosclerosis.2015.01.032. Epub 2015 Jan 31. Atherosclerosis. 2015. PMID: 25682028 Free PMC article.
347 results