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Type 1 diabetes genes and pathways shared by humans and NOD mice.
Wicker LS, Clark J, Fraser HI, Garner VE, Gonzalez-Munoz A, Healy B, Howlett S, Hunter K, Rainbow D, Rosa RL, Smink LJ, Todd JA, Peterson LB. Wicker LS, et al. Among authors: clark j. J Autoimmun. 2005;25 Suppl:29-33. doi: 10.1016/j.jaut.2005.09.009. Epub 2005 Oct 28. J Autoimmun. 2005. PMID: 16257508 Review.
Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse.
Wicker LS, Chamberlain G, Hunter K, Rainbow D, Howlett S, Tiffen P, Clark J, Gonzalez-Munoz A, Cumiskey AM, Rosa RL, Howson JM, Smink LJ, Kingsnorth A, Lyons PA, Gregory S, Rogers J, Todd JA, Peterson LB. Wicker LS, et al. Among authors: clark j. J Immunol. 2004 Jul 1;173(1):164-73. doi: 10.4049/jimmunol.173.1.164. J Immunol. 2004. PMID: 15210771
Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse.
Wicker LS, Moule CL, Fraser H, Penha-Goncalves C, Rainbow D, Garner VE, Chamberlain G, Hunter K, Howlett S, Clark J, Gonzalez-Munoz A, Cumiskey AM, Tiffen P, Howson J, Healy B, Smink LJ, Kingsnorth A, Lyons PA, Gregory S, Rogers J, Todd JA, Peterson LB. Wicker LS, et al. Among authors: clark j. Novartis Found Symp. 2005;267:57-65; discussion 65-75. doi: 10.1002/047002139x.ch6. Novartis Found Symp. 2005. PMID: 15999801
Evidence that Cd101 is an autoimmune diabetes gene in nonobese diabetic mice.
Rainbow DB, Moule C, Fraser HI, Clark J, Howlett SK, Burren O, Christensen M, Moody V, Steward CA, Mohammed JP, Fusakio ME, Masteller EL, Finger EB, Houchins JP, Naf D, Koentgen F, Ridgway WM, Todd JA, Bluestone JA, Peterson LB, Mattner J, Wicker LS. Rainbow DB, et al. Among authors: clark j. J Immunol. 2011 Jul 1;187(1):325-36. doi: 10.4049/jimmunol.1003523. Epub 2011 May 25. J Immunol. 2011. PMID: 21613616 Free PMC article.
Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice.
Fraser HI, Howlett S, Clark J, Rainbow DB, Stanford SM, Wu DJ, Hsieh YW, Maine CJ, Christensen M, Kuchroo V, Sherman LA, Podolin PL, Todd JA, Steward CA, Peterson LB, Bottini N, Wicker LS. Fraser HI, et al. Among authors: clark j. J Immunol. 2015 Nov 15;195(10):4841-52. doi: 10.4049/jimmunol.1402654. Epub 2015 Oct 5. J Immunol. 2015. PMID: 26438525 Free PMC article.
Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.
Yamanouchi J, Rainbow D, Serra P, Howlett S, Hunter K, Garner VE, Gonzalez-Munoz A, Clark J, Veijola R, Cubbon R, Chen SL, Rosa R, Cumiskey AM, Serreze DV, Gregory S, Rogers J, Lyons PA, Healy B, Smink LJ, Todd JA, Peterson LB, Wicker LS, Santamaria P. Yamanouchi J, et al. Among authors: clark j. Nat Genet. 2007 Mar;39(3):329-37. doi: 10.1038/ng1958. Epub 2007 Feb 4. Nat Genet. 2007. PMID: 17277778 Free PMC article.
Investigation of soluble and transmembrane CTLA-4 isoforms in serum and microvesicles.
Esposito L, Hunter KM, Clark J, Rainbow DB, Stevens H, Denesha J, Duley S, Dawson S, Coleman G, Nutland S, Bell GL, Moran C, Pekalski M, Todd JA, Wicker LS. Esposito L, et al. Among authors: clark j. J Immunol. 2014 Jul 15;193(2):889-900. doi: 10.4049/jimmunol.1303389. Epub 2014 Jun 13. J Immunol. 2014. PMID: 24928993 Free PMC article.
9,424 results