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Tolerance of high-dose (3,000 mg/day) coenzyme Q10 in ALS.
Ferrante KL, Shefner J, Zhang H, Betensky R, O'Brien M, Yu H, Fantasia M, Taft J, Beal MF, Traynor B, Newhall K, Donofrio P, Caress J, Ashburn C, Freiberg B, O'Neill C, Paladenech C, Walker T, Pestronk A, Abrams B, Florence J, Renna R, Schierbecker J, Malkus B, Cudkowicz M. Ferrante KL, et al. Among authors: zhang h. Neurology. 2005 Dec 13;65(11):1834-6. doi: 10.1212/01.wnl.0000187070.35365.d7. Neurology. 2005. PMID: 16344537 Clinical Trial.
Trial of celecoxib in amyotrophic lateral sclerosis.
Cudkowicz ME, Shefner JM, Schoenfeld DA, Zhang H, Andreasson KI, Rothstein JD, Drachman DB. Cudkowicz ME, et al. Among authors: zhang h. Ann Neurol. 2006 Jul;60(1):22-31. doi: 10.1002/ana.20903. Ann Neurol. 2006. PMID: 16802291 Clinical Trial.
Increased incidence of deep venous thrombosis in ALS.
Qureshi MM, Cudkowicz ME, Zhang H, Raynor E. Qureshi MM, et al. Among authors: zhang h. Neurology. 2007 Jan 2;68(1):76-7. doi: 10.1212/01.wnl.0000250444.30622.ee. Neurology. 2007. PMID: 17200499 No abstract available.
A clinical trial of creatine in ALS.
Shefner JM, Cudkowicz ME, Schoenfeld D, Conrad T, Taft J, Chilton M, Urbinelli L, Qureshi M, Zhang H, Pestronk A, Caress J, Donofrio P, Sorenson E, Bradley W, Lomen-Hoerth C, Pioro E, Rezania K, Ross M, Pascuzzi R, Heiman-Patterson T, Tandan R, Mitsumoto H, Rothstein J, Smith-Palmer T, MacDonald D, Burke D; NEALS Consortium. Shefner JM, et al. Among authors: zhang h. Neurology. 2004 Nov 9;63(9):1656-61. doi: 10.1212/01.wnl.0000142992.81995.f0. Neurology. 2004. PMID: 15534251 Clinical Trial.
Functional outcome measures as clinical trial endpoints in ALS.
Traynor BJ, Zhang H, Shefner JM, Schoenfeld D, Cudkowicz ME; NEALS Consortium. Traynor BJ, et al. Among authors: zhang h. Neurology. 2004 Nov 23;63(10):1933-5. doi: 10.1212/01.wnl.0000144345.49510.4e. Neurology. 2004. PMID: 15557515 Clinical Trial.
Maximum voluntary isometric contraction (MVIC).
Cudkowicz M, Zhang H, Qureshi M, Schoenfeld D. Cudkowicz M, et al. Among authors: zhang h. Amyotroph Lateral Scler Other Motor Neuron Disord. 2004 Sep;5 Suppl 1:84-5. doi: 10.1080/17434470410019744. Amyotroph Lateral Scler Other Motor Neuron Disord. 2004. PMID: 15512881 No abstract available.
Phase 2 study of sodium phenylbutyrate in ALS.
Cudkowicz ME, Andres PL, Macdonald SA, Bedlack RS, Choudry R, Brown RH Jr, Zhang H, Schoenfeld DA, Shefner J, Matson S, Matson WR, Ferrante RJ; Northeast ALS and National VA ALS Research Consortiums. Cudkowicz ME, et al. Among authors: zhang h. Amyotroph Lateral Scler. 2009 Apr;10(2):99-106. doi: 10.1080/17482960802320487. Amyotroph Lateral Scler. 2009. PMID: 18688762 Clinical Trial.
Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG.
Hersch SM, Gevorkian S, Marder K, Moskowitz C, Feigin A, Cox M, Como P, Zimmerman C, Lin M, Zhang L, Ulug AM, Beal MF, Matson W, Bogdanov M, Ebbel E, Zaleta A, Kaneko Y, Jenkins B, Hevelone N, Zhang H, Yu H, Schoenfeld D, Ferrante R, Rosas HD. Hersch SM, et al. Among authors: zhang l, zhang h. Neurology. 2006 Jan 24;66(2):250-2. doi: 10.1212/01.wnl.0000194318.74946.b6. Neurology. 2006. PMID: 16434666 Clinical Trial.
Paraoxonase 1 (PON1) organophosphate hydrolysis is not reduced in ALS.
Wills AM, Landers JE, Zhang H, Richter RJ, Caraganis AJ, Cudkowicz ME, Furlong CE, Brown RH Jr. Wills AM, et al. Among authors: zhang h. Neurology. 2008 Mar 18;70(12):929-34. doi: 10.1212/01.wnl.0000305956.37931.dd. Neurology. 2008. PMID: 18347314
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