Bouma G - Search Results

1

A partial down-regulation of WASP is sufficient to inhibit podosome formation in dendritic cells.

Olivier A, Jeanson-Leh L, Bouma G, Compagno D, Blondeau J, Seye K, Charrier S, Burns S, Thrasher AJ, Danos O, Vainchenker W, Galy A. Olivier A, et al. Among authors: bouma g. Mol Ther. 2006 Apr;13(4):729-37. doi: 10.1016/j.ymthe.2005.11.003. Epub 2005 Dec 15. Mol Ther. 2006. PMID: 16360341 Free article.

2

Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells.

Bouma G, Burns S, Thrasher AJ. Bouma G, et al. Blood. 2007 Dec 15;110(13):4278-84. doi: 10.1182/blood-2007-06-096875. Epub 2007 Aug 2. Blood. 2007. PMID: 17673604 Free article.

3

Stable gene transfer to muscle using non-integrating lentiviral vectors.

Apolonia L, Waddington SN, Fernandes C, Ward NJ, Bouma G, Blundell MP, Thrasher AJ, Collins MK, Philpott NJ. Apolonia L, et al. Among authors: bouma g. Mol Ther. 2007 Nov;15(11):1947-54. doi: 10.1038/sj.mt.6300281. Epub 2007 Aug 14. Mol Ther. 2007. PMID: 17700544 Free article.

4

Improvement of migratory defects in a murine model of Wiskott-Aldrich syndrome gene therapy.

Blundell MP, Bouma G, Calle Y, Jones GE, Kinnon C, Thrasher AJ. Blundell MP, et al. Among authors: bouma g. Mol Ther. 2008 May;16(5):836-44. doi: 10.1038/mt.2008.43. Epub 2008 Mar 18. Mol Ther. 2008. PMID: 18388921 Free article.

5

Wiskott-Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation.

Bouma G, Burns SO, Thrasher AJ. Bouma G, et al. Immunobiology. 2009;214(9-10):778-90. doi: 10.1016/j.imbio.2009.06.009. Epub 2009 Jul 22. Immunobiology. 2009. PMID: 19628299 Free PMC article. Review.

6

Cytoskeletal remodeling mediated by WASp in dendritic cells is necessary for normal immune synapse formation and T-cell priming.

Bouma G, Mendoza-Naranjo A, Blundell MP, de Falco E, Parsley KL, Burns SO, Thrasher AJ. Bouma G, et al. Blood. 2011 Sep 1;118(9):2492-501. doi: 10.1182/blood-2011-03-340265. Epub 2011 Jun 20. Blood. 2011. PMID: 21690559 Free article.

7

The Wiskott-Aldrich syndrome: The actin cytoskeleton and immune cell function.

Blundell MP, Worth A, Bouma G, Thrasher AJ. Blundell MP, et al. Among authors: bouma g. Dis Markers. 2010;29(3-4):157-75. doi: 10.3233/DMA-2010-0735. Dis Markers. 2010. PMID: 21178275 Free PMC article. Review.

8

Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration.

Worth AJ, Metelo J, Bouma G, Moulding D, Fritzsche M, Vernay B, Charras G, Cory GO, Thrasher AJ, Burns SO. Worth AJ, et al. Among authors: bouma g. Blood. 2013 Jan 3;121(1):72-84. doi: 10.1182/blood-2012-01-403857. Epub 2012 Nov 15. Blood. 2013. PMID: 23160469 Free PMC article.

9

Exacerbated experimental arthritis in Wiskott-Aldrich syndrome protein deficiency: modulatory role of regulatory B cells.

Bouma G, Carter NA, Recher M, Malinova D, Adriani M, Notarangelo LD, Burns SO, Mauri C, Thrasher AJ. Bouma G, et al. Eur J Immunol. 2014 Sep;44(9):2692-702. doi: 10.1002/eji.201344245. Epub 2014 Jul 15. Eur J Immunol. 2014. PMID: 24945741 Free PMC article. Clinical Trial.

10

Phosphorylation of WASp is a key regulator of activity and stability in vivo.

Blundell MP, Bouma G, Metelo J, Worth A, Calle Y, Cowell LA, Westerberg LS, Moulding DA, Mirando S, Kinnon C, Cory GO, Jones GE, Snapper SB, Burns SO, Thrasher AJ. Blundell MP, et al. Among authors: bouma g. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15738-43. doi: 10.1073/pnas.0904346106. Epub 2009 Sep 1. Proc Natl Acad Sci U S A. 2009. PMID: 19805221 Free PMC article.

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