Thrasher AJ - Search Results

1

A partial down-regulation of WASP is sufficient to inhibit podosome formation in dendritic cells.

Olivier A, Jeanson-Leh L, Bouma G, Compagno D, Blondeau J, Seye K, Charrier S, Burns S, Thrasher AJ, Danos O, Vainchenker W, Galy A. Olivier A, et al. Among authors: thrasher aj. Mol Ther. 2006 Apr;13(4):729-37. doi: 10.1016/j.ymthe.2005.11.003. Epub 2005 Dec 15. Mol Ther. 2006. PMID: 16360341 Free article.

2

Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells.

Bouma G, Burns S, Thrasher AJ. Bouma G, et al. Among authors: thrasher aj. Blood. 2007 Dec 15;110(13):4278-84. doi: 10.1182/blood-2007-06-096875. Epub 2007 Aug 2. Blood. 2007. PMID: 17673604 Free article.

3

Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients.

Charrier S, Dupré L, Scaramuzza S, Jeanson-Leh L, Blundell MP, Danos O, Cattaneo F, Aiuti A, Eckenberg R, Thrasher AJ, Roncarolo MG, Galy A. Charrier S, et al. Among authors: thrasher aj. Gene Ther. 2007 Mar;14(5):415-28. doi: 10.1038/sj.gt.3302863. Epub 2006 Oct 19. Gene Ther. 2007. PMID: 17051251

4

Validation of a mutated PRE sequence allowing high and sustained transgene expression while abrogating WHV-X protein synthesis: application to the gene therapy of WAS.

Zanta-Boussif MA, Charrier S, Brice-Ouzet A, Martin S, Opolon P, Thrasher AJ, Hope TJ, Galy A. Zanta-Boussif MA, et al. Among authors: thrasher aj. Gene Ther. 2009 May;16(5):605-19. doi: 10.1038/gt.2009.3. Epub 2009 Mar 5. Gene Ther. 2009. PMID: 19262615

5

Mechanisms of WASp-mediated hematologic and immunologic disease.

Burns S, Cory GO, Vainchenker W, Thrasher AJ. Burns S, et al. Among authors: thrasher aj. Blood. 2004 Dec 1;104(12):3454-62. doi: 10.1182/blood-2004-04-1678. Epub 2004 Aug 12. Blood. 2004. PMID: 15308573 Free article. Review.

6

Deficiency in the Wiskott-Aldrich protein induces premature proplatelet formation and platelet production in the bone marrow compartment.

Sabri S, Foudi A, Boukour S, Franc B, Charrier S, Jandrot-Perrus M, Farndale RW, Jalil A, Blundell MP, Cramer EM, Louache F, Debili N, Thrasher AJ, Vainchenker W. Sabri S, et al. Among authors: thrasher aj. Blood. 2006 Jul 1;108(1):134-40. doi: 10.1182/blood-2005-03-1219. Epub 2006 Mar 7. Blood. 2006. PMID: 16522820 Free article.

7

Stable gene transfer to muscle using non-integrating lentiviral vectors.

Apolonia L, Waddington SN, Fernandes C, Ward NJ, Bouma G, Blundell MP, Thrasher AJ, Collins MK, Philpott NJ. Apolonia L, et al. Among authors: thrasher aj. Mol Ther. 2007 Nov;15(11):1947-54. doi: 10.1038/sj.mt.6300281. Epub 2007 Aug 14. Mol Ther. 2007. PMID: 17700544 Free article.

8

Development of lentiviral gene therapy for Wiskott Aldrich syndrome.

Galy A, Roncarolo MG, Thrasher AJ. Galy A, et al. Among authors: thrasher aj. Expert Opin Biol Ther. 2008 Feb;8(2):181-90. doi: 10.1517/14712598.8.2.181. Expert Opin Biol Ther. 2008. PMID: 18194074 Free PMC article. Review.

9

Improvement of migratory defects in a murine model of Wiskott-Aldrich syndrome gene therapy.

Blundell MP, Bouma G, Calle Y, Jones GE, Kinnon C, Thrasher AJ. Blundell MP, et al. Among authors: thrasher aj. Mol Ther. 2008 May;16(5):836-44. doi: 10.1038/mt.2008.43. Epub 2008 Mar 18. Mol Ther. 2008. PMID: 18388921 Free article.

10

Wiskott-Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation.

Bouma G, Burns SO, Thrasher AJ. Bouma G, et al. Among authors: thrasher aj. Immunobiology. 2009;214(9-10):778-90. doi: 10.1016/j.imbio.2009.06.009. Epub 2009 Jul 22. Immunobiology. 2009. PMID: 19628299 Free PMC article. Review.

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