Horak E - Search Results

1

Isolation of scFvs to in vitro produced extracellular domains of EGFR family members.

Horak E, Heitner T, Robinson MK, Simmons HH, Garrison J, Russeva M, Furmanova P, Lou J, Zhou Y, Yuan QA, Weiner LM, Adams GP, Marks JD. Horak E, et al. Cancer Biother Radiopharm. 2005 Dec;20(6):603-13. doi: 10.1089/cbr.2005.20.603. Cancer Biother Radiopharm. 2005. PMID: 16398612

2

High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules.

Adams GP, Schier R, McCall AM, Simmons HH, Horak EM, Alpaugh RK, Marks JD, Weiner LM. Adams GP, et al. Among authors: horak em. Cancer Res. 2001 Jun 15;61(12):4750-5. Cancer Res. 2001. PMID: 11406547

3

A single treatment of yttrium-90-labeled CHX-A"-C6.5 diabody inhibits the growth of established human tumor xenografts in immunodeficient mice.

Adams GP, Shaller CC, Dadachova E, Simmons HH, Horak EM, Tesfaye A, Klein-Szanto AJ, Marks JD, Brechbiel MW, Weiner LM. Adams GP, et al. Among authors: horak em. Cancer Res. 2004 Sep 1;64(17):6200-6. doi: 10.1158/0008-5472.CAN-03-2382. Cancer Res. 2004. PMID: 15342405

4

Targeting ErbB2 and ErbB3 with a bispecific single-chain Fv enhances targeting selectivity and induces a therapeutic effect in vitro.

Robinson MK, Hodge KM, Horak E, Sundberg AL, Russeva M, Shaller CC, von Mehren M, Shchaveleva I, Simmons HH, Marks JD, Adams GP. Robinson MK, et al. Among authors: horak e. Br J Cancer. 2008 Nov 4;99(9):1415-25. doi: 10.1038/sj.bjc.6604700. Epub 2008 Oct 7. Br J Cancer. 2008. PMID: 18841159 Free PMC article.

5

Increasing the affinity for tumor antigen enhances bispecific antibody cytotoxicity.

McCall AM, Shahied L, Amoroso AR, Horak EM, Simmons HH, Nielson U, Adams GP, Schier R, Marks JD, Weiner LM. McCall AM, et al. Among authors: horak em. J Immunol. 2001 May 15;166(10):6112-7. doi: 10.4049/jimmunol.166.10.6112. J Immunol. 2001. PMID: 11342630

6

Isolation and characterization of an anti-CD16 single-chain Fv fragment and construction of an anti-HER2/neu/anti-CD16 bispecific scFv that triggers CD16-dependent tumor cytolysis.

McCall AM, Adams GP, Amoroso AR, Nielsen UB, Zhang L, Horak E, Simmons H, Schier R, Marks JD, Weiner LM. McCall AM, et al. Among authors: horak e. Mol Immunol. 1999 May;36(7):433-45. doi: 10.1016/s0161-5890(99)00057-7. Mol Immunol. 1999. PMID: 10449096

7

Delivery of the alpha-emitting radioisotope bismuth-213 to solid tumors via single-chain Fv and diabody molecules.

Adams GP, Shaller CC, Chappell LL, Wu C, Horak EM, Simmons HH, Litwin S, Marks JD, Weiner LM, Brechbiel MW. Adams GP, et al. Among authors: horak em. Nucl Med Biol. 2000 May;27(4):339-46. doi: 10.1016/s0969-8051(00)00103-7. Nucl Med Biol. 2000. PMID: 10938467

8

Effects of the tyrosine-kinase inhibitor geldanamycin on ligand-induced Her-2/neu activation, receptor expression and proliferation of Her-2-positive malignant cell lines.

Hartmann F, Horak EM, Cho C, Lupu R, Bolen JB, Stetler-Stevenson MA, Pfreundschuh M, Waldmann TA, Horak ID. Hartmann F, et al. Among authors: horak id, horak em. Int J Cancer. 1997 Jan 17;70(2):221-9. doi: 10.1002/(sici)1097-0215(19970117)70:2<221::aid-ijc14>3.0.co;2-l. Int J Cancer. 1997. PMID: 9009164 Free article.

9

Radioimmunotherapy targeting of HER2/neu oncoprotein on ovarian tumor using lead-212-DOTA-AE1.

Horak E, Hartmann F, Garmestani K, Wu C, Brechbiel M, Gansow OA, Landolfi NF, Waldmann TA. Horak E, et al. J Nucl Med. 1997 Dec;38(12):1944-50. J Nucl Med. 1997. PMID: 9430475 Free article.

10

Preparation and in vivo evaluation of linkers for 211At labeling of humanized anti-Tac.

Yordanov AT, Garmestani K, Zhang M, Zhang Z, Yao Z, Phillips KE, Herring B, Horak E, Beitzel MP, Schwarz UP, Gansow OA, Plascjak PS, Eckelman WC, Waldmann TA, Brechbiel MW. Yordanov AT, et al. Among authors: horak e. Nucl Med Biol. 2001 Oct;28(7):845-56. doi: 10.1016/s0969-8051(01)00257-8. Nucl Med Biol. 2001. PMID: 11578907

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