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Evidence for a dimeric assembly of two titin/telethonin complexes induced by the telethonin C-terminus.
Pinotsis N, Petoukhov M, Lange S, Svergun D, Zou P, Gautel M, Wilmanns M. Pinotsis N, et al. Among authors: lange s. J Struct Biol. 2006 Aug;155(2):239-50. doi: 10.1016/j.jsb.2006.03.028. Epub 2006 Apr 27. J Struct Biol. 2006. PMID: 16713295
Recently, we unraveled how the N-terminus of the longest filament component, the giant muscle protein titin, is assembled into an antiparallel (2:1) sandwich complex by the N-terminal titin-binding segment of the Z-disk ligand telethonin/T-cap [Zou, P., Pinotsis, N., Lange …
Recently, we unraveled how the N-terminus of the longest filament component, the giant muscle protein titin, is assembled into an antiparall …
The kinase domain of titin controls muscle gene expression and protein turnover.
Lange S, Xiang F, Yakovenko A, Vihola A, Hackman P, Rostkova E, Kristensen J, Brandmeier B, Franzen G, Hedberg B, Gunnarsson LG, Hughes SM, Marchand S, Sejersen T, Richard I, Edström L, Ehler E, Udd B, Gautel M. Lange S, et al. Science. 2005 Jun 10;308(5728):1599-603. doi: 10.1126/science.1110463. Epub 2005 Mar 31. Science. 2005. PMID: 15802564
The N2A region of titin has a unique structural configuration.
Stronczek C, Lange S, Bullard B, Wolniak S, Börgeson E, Mayans O, Fleming JR. Stronczek C, et al. Among authors: lange s. J Gen Physiol. 2021 Jul 5;153(7):e202012766. doi: 10.1085/jgp.202012766. J Gen Physiol. 2021. PMID: 33836065 Free PMC article.
The M-band: The underestimated part of the sarcomere.
Lange S, Pinotsis N, Agarkova I, Ehler E. Lange S, et al. Biochim Biophys Acta Mol Cell Res. 2020 Mar;1867(3):118440. doi: 10.1016/j.bbamcr.2019.02.003. Epub 2019 Feb 7. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 30738787 Free PMC article. Review.
1,436 results