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An attenuated mutant of the Rv1747 ATP-binding cassette transporter of Mycobacterium tuberculosis and a mutant of its cognate kinase, PknF, show increased expression of the efflux pump-related iniBAC operon.
Spivey VL, Whalan RH, Hirst EM, Smerdon SJ, Buxton RS. Spivey VL, et al. Among authors: whalan rh. FEMS Microbiol Lett. 2013 Oct;347(2):107-15. doi: 10.1111/1574-6968.12230. Epub 2013 Aug 23. FEMS Microbiol Lett. 2013. PMID: 23915284 Free PMC article.
A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of the rpfA gene coding for a resuscitation promoting factor.
Rickman L, Scott C, Hunt DM, Hutchinson T, Menéndez MC, Whalan R, Hinds J, Colston MJ, Green J, Buxton RS. Rickman L, et al. Mol Microbiol. 2005 Jun;56(5):1274-86. doi: 10.1111/j.1365-2958.2005.04609.x. Mol Microbiol. 2005. PMID: 15882420 Free PMC article.
Transposon mutagenesis in Clostridium difficile.
Hussain HA, Roberts AP, Whalan R, Mullany P. Hussain HA, et al. Methods Mol Biol. 2010;646:203-11. doi: 10.1007/978-1-60327-365-7_13. Methods Mol Biol. 2010. PMID: 20597011