Comparisons of site- and haplotype-frequency methods for detecting positive selection.
Zeng K, Mano S, Shi S, Wu CI.
Zeng K, et al.
Mol Biol Evol. 2007 Jul;24(7):1562-74. doi: 10.1093/molbev/msm078. Epub 2007 Apr 21.
Mol Biol Evol. 2007.
PMID: 17449894
Our results are the following. 1) Although haplotype-frequency tests that are conditional on the number of haplotypes (K) were developed for nonrecombining haplotypes, these tests are insensitive to recombination. ...To alleviate the problem of low specificity, compound te …
Our results are the following. 1) Although haplotype-frequency tests that are conditional on the number of haplotypes (K) were develo …