Kwak MK - Search Results

1

Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole.

Yates MS, Kwak MK, Egner PA, Groopman JD, Bodreddigari S, Sutter TR, Baumgartner KJ, Roebuck BD, Liby KT, Yore MM, Honda T, Gribble GW, Sporn MB, Kensler TW. Yates MS, et al. Among authors: kwak mk. Cancer Res. 2006 Feb 15;66(4):2488-94. doi: 10.1158/0008-5472.CAN-05-3823. Cancer Res. 2006. PMID: 16489057

2

Chemoprevention through the Keap1-Nrf2 signaling pathway by phase 2 enzyme inducers.

Kwak MK, Wakabayashi N, Kensler TW. Kwak MK, et al. Mutat Res. 2004 Nov 2;555(1-2):133-48. doi: 10.1016/j.mrfmmm.2004.06.041. Mutat Res. 2004. PMID: 15476857 Review.

3

Role of phase 2 enzyme induction in chemoprotection by dithiolethiones.

Kwak MK, Egner PA, Dolan PM, Ramos-Gomez M, Groopman JD, Itoh K, Yamamoto M, Kensler TW. Kwak MK, et al. Mutat Res. 2001 Sep 1;480-481:305-15. doi: 10.1016/s0027-5107(01)00190-7. Mutat Res. 2001. PMID: 11506823 Review.

4

Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter.

Kwak MK, Itoh K, Yamamoto M, Kensler TW. Kwak MK, et al. Mol Cell Biol. 2002 May;22(9):2883-92. doi: 10.1128/MCB.22.9.2883-2892.2002. Mol Cell Biol. 2002. PMID: 11940647 Free PMC article.

5

Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.

Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yamamoto M, Kensler TW. Kwak MK, et al. J Biol Chem. 2003 Mar 7;278(10):8135-45. doi: 10.1074/jbc.M211898200. Epub 2002 Dec 27. J Biol Chem. 2003. PMID: 12506115 Free article.

6

Induction of phase 2 enzymes by serum oxidized polyamines through activation of Nrf2: effect of the polyamine metabolite acrolein.

Kwak MK, Kensler TW, Casero RA Jr. Kwak MK, et al. Biochem Biophys Res Commun. 2003 Jun 6;305(3):662-70. doi: 10.1016/s0006-291x(03)00834-9. Biochem Biophys Res Commun. 2003. PMID: 12763045

7

Phase 2 enzyme induction by the major metabolite of oltipraz.

Petzer JP, Navamal M, Johnson JK, Kwak MK, Kensler TW, Fishbein JC. Petzer JP, et al. Among authors: kwak mk. Chem Res Toxicol. 2003 Nov;16(11):1463-9. doi: 10.1021/tx034154e. Chem Res Toxicol. 2003. PMID: 14615973

8

Chemoprevention by 1,2-dithiole-3-thiones through induction of NQO1 and other phase 2 enzymes.

Kwak MK, Ramos-Gomez M, Wakabayashi N, Kensler TW. Kwak MK, et al. Methods Enzymol. 2004;382:414-23. doi: 10.1016/S0076-6879(04)82022-6. Methods Enzymol. 2004. PMID: 15047114 Review. No abstract available.

9

Targeting NRF2 signaling for cancer chemoprevention.

Kwak MK, Kensler TW. Kwak MK, et al. Toxicol Appl Pharmacol. 2010 Apr 1;244(1):66-76. doi: 10.1016/j.taap.2009.08.028. Epub 2009 Sep 2. Toxicol Appl Pharmacol. 2010. PMID: 19732782 Free PMC article. Review.

10

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.

Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M, Talalay P, Kensler TW. Ramos-Gomez M, et al. Among authors: kwak mk. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3410-5. doi: 10.1073/pnas.051618798. Proc Natl Acad Sci U S A. 2001. PMID: 11248092 Free PMC article.

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