Tkachenko S - Search Results

1

Screening for caspase-3 inhibitors: a new class of potent small-molecule inhibitors of caspase-3.

Okun I, Malarchuk S, Dubrovskaya E, Khvat A, Tkachenko S, Kysil V, Ilyin A, Kravchenko D, Prossnitz ER, Sklar L, Ivachtchenko A. Okun I, et al. Among authors: tkachenko s. J Biomol Screen. 2006 Apr;11(3):277-85. doi: 10.1177/1087057105285048. Epub 2006 Feb 20. J Biomol Screen. 2006. PMID: 16490769

2

Screening for caspase-3 inhibitors: effect of a reducing agent on identified hit chemotypes.

Okun I, Malarchuk S, Dubrovskaya E, Khvat A, Tkachenko S, Kysil V, Kravchenko D, Ivachtchenko A. Okun I, et al. Among authors: tkachenko s. J Biomol Screen. 2006 Sep;11(6):694-703. doi: 10.1177/1087057106289231. Epub 2006 Jul 14. J Biomol Screen. 2006. PMID: 16844966

3

Pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. Synthesis and SAR of 2-substituted 4-methyl-8-(morpholine-4-sulfonyl)-pyrrolo[3,4-c]quinoline-1,3-diones.

Kravchenko DV, Kysil VM, Tkachenko SE, Maliarchouk S, Okun IM, Ivachtchenko AV. Kravchenko DV, et al. Among authors: tkachenko se. Eur J Med Chem. 2005 Dec;40(12):1377-83. doi: 10.1016/j.ejmech.2005.07.011. Epub 2005 Sep 15. Eur J Med Chem. 2005. PMID: 16169127

4

Synthesis and caspase-3 inhibitory activity of 8-sulfonyl-1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]quinolines.

Kravchenko DV, Kysil VM, Tkachenko SE, Maliarchouk S, Okun IM, Ivachtchenko AV. Kravchenko DV, et al. Among authors: tkachenko se. Farmaco. 2005 Oct;60(10):804-9. doi: 10.1016/j.farmac.2005.08.001. Epub 2005 Sep 21. Farmaco. 2005. PMID: 16182295

5

Caspase activity modulators as anticancer agents.

Okun I, Balakin KV, Tkachenko SE, Ivachtchenko AV. Okun I, et al. Anticancer Agents Med Chem. 2008 Apr;8(3):322-41. doi: 10.2174/187152008783961914. Anticancer Agents Med Chem. 2008. PMID: 18393791 Review.

6

1,3-Dioxo-4-methyl-2,3-dihydro-1H-pyrrolo[3,4-c]quinolines as potent caspase-3 inhibitors.

Kravchenko DV, Kysil VV, Ilyn AP, Tkachenko SE, Maliarchouk S, Okun IM, Ivachtchenko AV. Kravchenko DV, et al. Among authors: tkachenko se. Bioorg Med Chem Lett. 2005 Apr 1;15(7):1841-5. doi: 10.1016/j.bmcl.2005.02.027. Bioorg Med Chem Lett. 2005. PMID: 15780618

7

Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8-(morpholine-4-sulfonyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors.

Kravchenko DV, Kuzovkova YA, Kysil VM, Tkachenko SE, Maliarchouk S, Okun IM, Balakin KV, Ivachtchenko AV. Kravchenko DV, et al. Among authors: tkachenko se. J Med Chem. 2005 Jun 2;48(11):3680-3. doi: 10.1021/jm048987t. J Med Chem. 2005. PMID: 15916416

8

Small-molecule modulators of Hh and Wnt signaling pathways.

Kiselyov AS, Tkachenko SE, Balakin KV, Ivachtchenko AV. Kiselyov AS, et al. Among authors: tkachenko se. Expert Opin Ther Targets. 2007 Aug;11(8):1087-101. doi: 10.1517/14728222.11.8.1087. Expert Opin Ther Targets. 2007. PMID: 17665980 Review.

9

Novel mitotic targets and their small-molecule inhibitors.

Ivachtchenko AV, Kiselyov AS, Tkachenko SE, Ivanenkov YA, Balakin KV. Ivachtchenko AV, et al. Among authors: tkachenko se. Curr Cancer Drug Targets. 2007 Dec;7(8):766-84. doi: 10.2174/156800907783220499. Curr Cancer Drug Targets. 2007. PMID: 18220536 Review.

10

Synthesis and biological evaluation of novel gamma-carboline analogues of Dimebon as potent 5-HT6 receptor antagonists.

Ivachtchenko AV, Frolov EB, Mitkin OD, Kysil VM, Khvat AV, Okun IM, Tkachenko SE. Ivachtchenko AV, et al. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3183-7. doi: 10.1016/j.bmcl.2009.04.128. Epub 2009 May 3. Bioorg Med Chem Lett. 2009. PMID: 19443217

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