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Potent inhibitors of Huntingtin protein aggregation in a cell-based assay.
Rinderspacher A, Cremona ML, Liu Y, Deng SX, Xie Y, Gong G, Aulner N, Többen U, Myers K, Chung C, Andersen M, Vidović D, Schürer S, Brandén L, Yamamoto A, Landry DW. Rinderspacher A, et al. Among authors: yamamoto a. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1715-7. doi: 10.1016/j.bmcl.2009.01.087. Epub 2009 Jan 30. Bioorg Med Chem Lett. 2009. PMID: 19243939 Free PMC article.
Acetylation targets mutant huntingtin to autophagosomes for degradation.
Jeong H, Then F, Melia TJ Jr, Mazzulli JR, Cui L, Savas JN, Voisine C, Paganetti P, Tanese N, Hart AC, Yamamoto A, Krainc D. Jeong H, et al. Among authors: yamamoto a. Cell. 2009 Apr 3;137(1):60-72. doi: 10.1016/j.cell.2009.03.018. Cell. 2009. PMID: 19345187 Free PMC article.
A role for autophagy in Huntington's disease.
Croce KR, Yamamoto A. Croce KR, et al. Among authors: yamamoto a. Neurobiol Dis. 2019 Feb;122:16-22. doi: 10.1016/j.nbd.2018.08.010. Epub 2018 Aug 24. Neurobiol Dis. 2019. PMID: 30149183 Free PMC article. Review.
4,336 results