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The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation.
Jamieson CH, Gotlib J, Durocher JA, Chao MP, Mariappan MR, Lay M, Jones C, Zehnder JL, Lilleberg SL, Weissman IL. Jamieson CH, et al. Among authors: durocher ja. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6224-9. doi: 10.1073/pnas.0601462103. Epub 2006 Apr 7. Proc Natl Acad Sci U S A. 2006. PMID: 16603627 Free PMC article.
Glycogen synthase kinase 3beta missplicing contributes to leukemia stem cell generation.
Abrahamsson AE, Geron I, Gotlib J, Dao KH, Barroga CF, Newton IG, Giles FJ, Durocher J, Creusot RS, Karimi M, Jones C, Zehnder JL, Keating A, Negrin RS, Weissman IL, Jamieson CH. Abrahamsson AE, et al. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3925-9. doi: 10.1073/pnas.0900189106. Epub 2009 Feb 23. Proc Natl Acad Sci U S A. 2009. PMID: 19237556 Free PMC article.
Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation.
Gotlib J, Berubé C, Growney JD, Chen CC, George TI, Williams C, Kajiguchi T, Ruan J, Lilleberg SL, Durocher JA, Lichy JH, Wang Y, Cohen PS, Arber DA, Heinrich MC, Neckers L, Galli SJ, Gilliland DG, Coutré SE. Gotlib J, et al. Among authors: durocher ja. Blood. 2005 Oct 15;106(8):2865-70. doi: 10.1182/blood-2005-04-1568. Epub 2005 Jun 21. Blood. 2005. PMID: 15972446 Free PMC article.
Mutation detection using Surveyor nuclease.
Qiu P, Shandilya H, D'Alessio JM, O'Connor K, Durocher J, Gerard GF. Qiu P, et al. Biotechniques. 2004 Apr;36(4):702-7. doi: 10.2144/04364PF01. Biotechniques. 2004. PMID: 15088388 Free article.
Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors.
Nickerson ML, Jaeger E, Shi Y, Durocher JA, Mahurkar S, Zaridze D, Matveev V, Janout V, Kollarova H, Bencko V, Navratilova M, Szeszenia-Dabrowska N, Mates D, Mukeria A, Holcatova I, Schmidt LS, Toro JR, Karami S, Hung R, Gerard GF, Linehan WM, Merino M, Zbar B, Boffetta P, Brennan P, Rothman N, Chow WH, Waldman FM, Moore LE. Nickerson ML, et al. Among authors: durocher ja. Clin Cancer Res. 2008 Aug 1;14(15):4726-34. doi: 10.1158/1078-0432.CCR-07-4921. Clin Cancer Res. 2008. PMID: 18676741 Free PMC article.