Monks BG - Search Results

1

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.

Rowe DC, McGettrick AF, Latz E, Monks BG, Gay NJ, Yamamoto M, Akira S, O'Neill LA, Fitzgerald KA, Golenbock DT. Rowe DC, et al. Among authors: monks bg. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6299-304. doi: 10.1073/pnas.0510041103. Epub 2006 Apr 7. Proc Natl Acad Sci U S A. 2006. PMID: 16603631 Free PMC article.

2

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.

Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, Latz E, Monks B, Pitha PM, Golenbock DT. Fitzgerald KA, et al. J Exp Med. 2003 Oct 6;198(7):1043-55. doi: 10.1084/jem.20031023. Epub 2003 Sep 29. J Exp Med. 2003. PMID: 14517278 Free PMC article.

3

Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.

Latz E, Visintin A, Lien E, Fitzgerald KA, Monks BG, Kurt-Jones EA, Golenbock DT, Espevik T. Latz E, et al. Among authors: monks bg. J Biol Chem. 2002 Dec 6;277(49):47834-43. doi: 10.1074/jbc.M207873200. Epub 2002 Sep 24. J Biol Chem. 2002. PMID: 12324469 Free article.

4

Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.

Visintin A, Latz E, Monks BG, Espevik T, Golenbock DT. Visintin A, et al. Among authors: monks bg. J Biol Chem. 2003 Nov 28;278(48):48313-20. doi: 10.1074/jbc.M306802200. Epub 2003 Sep 5. J Biol Chem. 2003. PMID: 12960171 Free article.

5

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

Parroche P, Lauw FN, Goutagny N, Latz E, Monks BG, Visintin A, Halmen KA, Lamphier M, Olivier M, Bartholomeu DC, Gazzinelli RT, Golenbock DT. Parroche P, et al. Among authors: monks bg. Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1919-24. doi: 10.1073/pnas.0608745104. Epub 2007 Jan 29. Proc Natl Acad Sci U S A. 2007. PMID: 17261807 Free PMC article.

6

A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.

Nagpal K, Plantinga TS, Wong J, Monks BG, Gay NJ, Netea MG, Fitzgerald KA, Golenbock DT. Nagpal K, et al. Among authors: monks bg. J Biol Chem. 2009 Sep 18;284(38):25742-8. doi: 10.1074/jbc.M109.014886. Epub 2009 Jun 9. J Biol Chem. 2009. PMID: 19509286 Free PMC article.

7

Cell distributions and functions of Toll-like receptor 4 studied by fluorescent gene constructs.

Espevik T, Latz E, Lien E, Monks B, Golenbock DT. Espevik T, et al. Scand J Infect Dis. 2003;35(9):660-4. doi: 10.1080/00365540310016493. Scand J Infect Dis. 2003. PMID: 14620151 Review.

8

TLR9 signals after translocating from the ER to CpG DNA in the lysosome.

Latz E, Schoenemeyer A, Visintin A, Fitzgerald KA, Monks BG, Knetter CF, Lien E, Nilsen NJ, Espevik T, Golenbock DT. Latz E, et al. Among authors: monks bg. Nat Immunol. 2004 Feb;5(2):190-8. doi: 10.1038/ni1028. Epub 2004 Jan 11. Nat Immunol. 2004. PMID: 14716310

9

The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

Rothenfusser S, Goutagny N, DiPerna G, Gong M, Monks BG, Schoenemeyer A, Yamamoto M, Akira S, Fitzgerald KA. Rothenfusser S, et al. Among authors: monks bg. J Immunol. 2005 Oct 15;175(8):5260-8. doi: 10.4049/jimmunol.175.8.5260. J Immunol. 2005. PMID: 16210631

10

Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.

Visintin A, Halmen KA, Latz E, Monks BG, Golenbock DT. Visintin A, et al. Among authors: monks bg. J Immunol. 2005 Nov 15;175(10):6465-72. doi: 10.4049/jimmunol.175.10.6465. J Immunol. 2005. PMID: 16272300

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