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Heterozygous mutation within a kinase-conserved motif of the insulin-like growth factor I receptor causes intrauterine and postnatal growth retardation.
Kruis T, Klammt J, Galli-Tsinopoulou A, Wallborn T, Schlicke M, Müller E, Kratzsch J, Körner A, Odeh R, Kiess W, Pfäffle R. Kruis T, et al. Among authors: klammt j. J Clin Endocrinol Metab. 2010 Mar;95(3):1137-42. doi: 10.1210/jc.2009-1433. Epub 2010 Jan 26. J Clin Endocrinol Metab. 2010. PMID: 20103656
A role for leptin in sexual maturation and puberty?
Kiess W, Reich A, Meyer K, Glasow A, Deutscher J, Klammt J, Yang Y, Müller G, Kratzsch J. Kiess W, et al. Among authors: klammt j. Horm Res. 1999;51 Suppl 3:55-63. doi: 10.1159/000053163. Horm Res. 1999. PMID: 10592445 Review.
Clinical examples of disturbed IGF signaling: intrauterine and postnatal growth retardation due to mutations of the insulin-like growth factor I receptor (IGF-IR) gene.
Kiess W, Kratzsch J, Keller E, Schneider A, Raile K, Klammt J, Seidel B, Garten A, Schmidt H, Pfäffle R. Kiess W, et al. Among authors: klammt j. Rev Endocr Metab Disord. 2005 Aug;6(3):183-7. doi: 10.1007/s11154-005-3049-5. Rev Endocr Metab Disord. 2005. PMID: 16151622 No abstract available.
Downstream insulin-like growth factor.
Pfäffle R, Kiess W, Klammt J. Pfäffle R, et al. Among authors: klammt j. Endocr Dev. 2012;23:42-51. doi: 10.1159/000341745. Epub 2012 Nov 23. Endocr Dev. 2012. PMID: 23182819 Review.
84 results