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Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines.
Liu Y, Shin S, Zeng X, Zhan M, Gonzalez R, Mueller FJ, Schwartz CM, Xue H, Li H, Baker SC, Chudin E, Barker DL, McDaniel TK, Oeser S, Loring JF, Mattson MP, Rao MS. Liu Y, et al. Among authors: gonzalez r. BMC Dev Biol. 2006 May 3;6:20. doi: 10.1186/1471-213X-6-20. BMC Dev Biol. 2006. PMID: 16672070 Free PMC article.
Human embryonic stem cells have a unique epigenetic signature.
Bibikova M, Chudin E, Wu B, Zhou L, Garcia EW, Liu Y, Shin S, Plaia TW, Auerbach JM, Arking DE, Gonzalez R, Crook J, Davidson B, Schulz TC, Robins A, Khanna A, Sartipy P, Hyllner J, Vanguri P, Savant-Bhonsale S, Smith AK, Chakravarti A, Maitra A, Rao M, Barker DL, Loring JF, Fan JB. Bibikova M, et al. Among authors: gonzalez r. Genome Res. 2006 Sep;16(9):1075-83. doi: 10.1101/gr.5319906. Epub 2006 Aug 9. Genome Res. 2006. PMID: 16899657 Free PMC article.
Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease.
Lee JP, Jeyakumar M, Gonzalez R, Takahashi H, Lee PJ, Baek RC, Clark D, Rose H, Fu G, Clarke J, McKercher S, Meerloo J, Muller FJ, Park KI, Butters TD, Dwek RA, Schwartz P, Tong G, Wenger D, Lipton SA, Seyfried TN, Platt FM, Snyder EY. Lee JP, et al. Among authors: gonzalez r. Nat Med. 2007 Apr;13(4):439-47. doi: 10.1038/nm1548. Epub 2007 Mar 11. Nat Med. 2007. PMID: 17351625
Dorsomorphin promotes human embryonic stem cell self-renewal.
Gonzalez R, Lee JW, Snyder EY, Schultz PG. Gonzalez R, et al. Angew Chem Int Ed Engl. 2011 Apr 4;50(15):3439-41. doi: 10.1002/anie.201005659. Epub 2011 Mar 7. Angew Chem Int Ed Engl. 2011. PMID: 21384475 No abstract available.
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells.
Redmond DE Jr, Bjugstad KB, Teng YD, Ourednik V, Ourednik J, Wakeman DR, Parsons XH, Gonzalez R, Blanchard BC, Kim SU, Gu Z, Lipton SA, Markakis EA, Roth RH, Elsworth JD, Sladek JR Jr, Sidman RL, Snyder EY. Redmond DE Jr, et al. Among authors: gonzalez r. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12175-80. doi: 10.1073/pnas.0704091104. Epub 2007 Jun 22. Proc Natl Acad Sci U S A. 2007. PMID: 17586681 Free PMC article.
Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency.
Gonzalez R, Jennings LL, Knuth M, Orth AP, Klock HE, Ou W, Feuerhelm J, Hull MV, Koesema E, Wang Y, Zhang J, Wu C, Cho CY, Su AI, Batalov S, Chen H, Johnson K, Laffitte B, Nguyen DG, Snyder EY, Schultz PG, Harris JL, Lesley SA. Gonzalez R, et al. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3552-7. doi: 10.1073/pnas.0914019107. Epub 2010 Feb 2. Proc Natl Acad Sci U S A. 2010. PMID: 20133595 Free PMC article.
Deriving dopaminergic neurons for clinical use. A practical approach.
Gonzalez R, Garitaonandia I, Abramihina T, Wambua GK, Ostrowska A, Brock M, Noskov A, Boscolo FS, Craw JS, Laurent LC, Snyder EY, Semechkin RA. Gonzalez R, et al. Sci Rep. 2013;3:1463. doi: 10.1038/srep01463. Sci Rep. 2013. PMID: 23492920 Free PMC article.
4,682 results