Clark A - Search Results

1

The variable number of tandem repeats upstream of the insulin gene is a susceptibility locus for latent autoimmune diabetes in adults.

Desai M, Zeggini E, Horton VA, Owen KR, Hattersley AT, Levy JC, Hitman GA, Walker M, Holman RR, McCarthy MI, Clark A. Desai M, et al. Among authors: clark a. Diabetes. 2006 Jun;55(6):1890-4. doi: 10.2337/db06-0089. Diabetes. 2006. PMID: 16731859

2

Evidence that an isoform of calpain-10 is a regulator of exocytosis in pancreatic beta-cells.

Marshall C, Hitman GA, Partridge CJ, Clark A, Ma H, Shearer TR, Turner MD. Marshall C, et al. Among authors: clark a. Mol Endocrinol. 2005 Jan;19(1):213-24. doi: 10.1210/me.2004-0064. Epub 2004 Oct 7. Mol Endocrinol. 2005. PMID: 15471947

3

Islet amyloid polypeptide gene promoter polymorphisms are not associated with Type 2 diabetes or with the severity of islet amyloidosis.

Esapa C, Moffitt JH, Novials A, McNamara CM, Levy JC, Laakso M, Gomis R, Clark A. Esapa C, et al. Among authors: clark a. Biochim Biophys Acta. 2005 Apr 15;1740(1):74-8. doi: 10.1016/j.bbadis.2005.02.001. Epub 2005 Feb 23. Biochim Biophys Acta. 2005. PMID: 15878744 Free article.

4

Calpain facilitates actin reorganization during glucose-stimulated insulin secretion.

Turner MD, Fulcher FK, Jones CV, Smith BT, Aganna E, Partridge CJ, Hitman GA, Clark A, Patel YM. Turner MD, et al. Among authors: clark a. Biochem Biophys Res Commun. 2007 Jan 19;352(3):650-5. doi: 10.1016/j.bbrc.2006.11.077. Epub 2006 Nov 29. Biochem Biophys Res Commun. 2007. PMID: 17150188

5

Identification of the amyloid-degrading enzyme neprilysin in mouse islets and potential role in islet amyloidogenesis.

Zraika S, Hull RL, Udayasankar J, Clark A, Utzschneider KM, Tong J, Gerchman F, Kahn SE. Zraika S, et al. Among authors: clark a. Diabetes. 2007 Feb;56(2):304-10. doi: 10.2337/db06-0430. Diabetes. 2007. PMID: 17259373

6

Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles.

Collins SC, Hoppa MB, Walker JN, Amisten S, Abdulkader F, Bengtsson M, Fearnside J, Ramracheya R, Toye AA, Zhang Q, Clark A, Gauguier D, Rorsman P. Collins SC, et al. Among authors: clark a. Diabetes. 2010 May;59(5):1192-201. doi: 10.2337/db09-0791. Epub 2010 Feb 11. Diabetes. 2010. PMID: 20150285 Free PMC article.

7

Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells.

Braun M, Ramracheya R, Bengtsson M, Clark A, Walker JN, Johnson PR, Rorsman P. Braun M, et al. Among authors: clark a. Diabetes. 2010 Jul;59(7):1694-701. doi: 10.2337/db09-0797. Epub 2010 Apr 22. Diabetes. 2010. PMID: 20413510 Free PMC article.

8

Loss of β-Cell Identity Occurs in Type 2 Diabetes and Is Associated With Islet Amyloid Deposits.

Spijker HS, Song H, Ellenbroek JH, Roefs MM, Engelse MA, Bos E, Koster AJ, Rabelink TJ, Hansen BC, Clark A, Carlotti F, de Koning EJ. Spijker HS, et al. Among authors: clark a. Diabetes. 2015 Aug;64(8):2928-38. doi: 10.2337/db14-1752. Epub 2015 Apr 27. Diabetes. 2015. PMID: 25918235 Free article.

9

Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells.

Thomsen SK, Raimondo A, Hastoy B, Sengupta S, Dai XQ, Bautista A, Censin J, Payne AJ, Umapathysivam MM, Spigelman AF, Barrett A, Groves CJ, Beer NL, Manning Fox JE, McCarthy MI, Clark A, Mahajan A, Rorsman P, MacDonald PE, Gloyn AL. Thomsen SK, et al. Among authors: clark a. Nat Genet. 2018 Aug;50(8):1122-1131. doi: 10.1038/s41588-018-0173-1. Epub 2018 Jul 27. Nat Genet. 2018. PMID: 30054598 Free PMC article.

10

β-cell secretory dysfunction: a key cause of type 2 diabetes.

Holman RR, Clark A, Rorsman P. Holman RR, et al. Among authors: clark a. Lancet Diabetes Endocrinol. 2020 May;8(5):370. doi: 10.1016/S2213-8587(20)30119-4. Lancet Diabetes Endocrinol. 2020. PMID: 32333873 No abstract available.

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