Yan KX - Search Results

1

Absorption, metabolism, and excretion of [14C]MK-0767 (2-methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in humans.

Kochansky CJ, Rippley RK, Yan KX, Song H, Wallace MA, Dean D, Jones AN, Lasseter K, Schwartz J, Vincent SH, Franklin RB, Wagner J. Kochansky CJ, et al. Among authors: yan kx. Drug Metab Dispos. 2006 Sep;34(9):1457-61. doi: 10.1124/dmd.106.010231. Epub 2006 Jun 13. Drug Metab Dispos. 2006. PMID: 16772365 Clinical Trial.

2

Determination of MK-0767 enantiomers in human plasma by normal phase LC-MS/MS.

Yan KX, Song H, Lo MW. Yan KX, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Dec 25;813(1-2):95-102. doi: 10.1016/j.jchromb.2004.09.016. J Chromatogr B Analyt Technol Biomed Life Sci. 2004. PMID: 15556521

3

Human pharmacokinetics and interconversion of enantiomers of MK-0767, a dual PPARalpha/gamma agonist.

Rippley RK, Yan KX, Matthews ND, Greenberg HE, Herman GA, Wagner JA. Rippley RK, et al. Among authors: yan kx. J Clin Pharmacol. 2007 Mar;47(3):323-33. doi: 10.1177/0091270006297141. J Clin Pharmacol. 2007. PMID: 17322144 Clinical Trial.

4

Quantitative determination of MK-0767, a dual alpha/gamma peroxisome proliferator-activated receptor (PPAR) agonist, in human plasma by liquid chromatography-tandem mass spectrometry.

Song H, Yan K, Xu X, Lo MW. Song H, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Oct 15;810(1):7-13. doi: 10.1016/j.jchromb.2004.07.003. J Chromatogr B Analyt Technol Biomed Life Sci. 2004. PMID: 15358302

5

Quantitative determination of a novel dual PPAR alpha/gamma agonist using on-line turbulent flow extraction with liquid chromatography-tandem mass spectrometry.

Xu XS, Yan KX, Song H, Lo MW. Xu XS, et al. Among authors: yan kx. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jan 5;814(1):29-36. doi: 10.1016/j.jchromb.2004.09.033. J Chromatogr B Analyt Technol Biomed Life Sci. 2005. PMID: 15675045

6

A dual PPAR alpha/gamma agonist increases adiponectin and improves plasma lipid profiles in healthy subjects.

Decochez K, Rippley RK, Miller JL, De Smet M, Yan KX, Matthijs Z, Riffel KA, Song H, Zhu H, Maynor HO, Tanaka W, Johnson-Levonas AO, Davies MJ, Gottesdiener KM, Keymeulen B, Wagner JA. Decochez K, et al. Among authors: yan kx. Drugs R D. 2006;7(2):99-110. doi: 10.2165/00126839-200607020-00004. Drugs R D. 2006. PMID: 16542056 Clinical Trial.

7

Simultaneous determination of a novel M3 muscarinic receptor antagonist and its active 5-OH metabolite in human plasma using liquid chromatography/tandem mass spectrometry.

Yan KX, Song H, Riffel K, Lo MW. Yan KX, et al. J Pharm Biomed Anal. 2002 Feb 1;27(5):699-709. doi: 10.1016/s0731-7085(01)00636-7. J Pharm Biomed Anal. 2002. PMID: 11814711

8

Simultaneous determination of a novel thrombin inhibitor and its two metabolites in human plasma by liquid chromatography/tandem mass spectrometry.

Riffel KA, Song H, Gu X, Yan K, Lo MW. Riffel KA, et al. J Pharm Biomed Anal. 2000 Aug 15;23(2-3):607-16. doi: 10.1016/s0731-7085(00)00353-8. J Pharm Biomed Anal. 2000. PMID: 10933555

9

Determination of a novel thrombin inhibitor in human plasma and urine utilizing liquid chromatography with tandem mass spectrometric and ultraviolet detection.

Song H, Gu X, Riffel K, Yan K, Lo MW. Song H, et al. J Chromatogr B Biomed Sci Appl. 2000 Jan 28;738(1):83-91. doi: 10.1016/s0378-4347(99)00491-0. J Chromatogr B Biomed Sci Appl. 2000. PMID: 10778929

10

Pharmacokinetic-pharmacodynamic studies of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor MK-0916 in healthy subjects.

Wright DH, Stone JA, Crumley TM, Wenning L, Zheng W, Yan K, Yang AY, Sun L, Cilissen C, Ramael S, Hermanowski-Vosatka A, Langdon RB, Gottesdiener KM, Wagner JA, Lai E. Wright DH, et al. Br J Clin Pharmacol. 2013 Dec;76(6):917-31. doi: 10.1111/bcp.12131. Br J Clin Pharmacol. 2013. PMID: 23594227 Free PMC article. Clinical Trial.

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