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Residues 207, 216, and 221 and the catalytic activity of mGSTA1-1 and mGSTA2-2 toward benzo[a]pyrene-(7R,8S)-diol-(9S,10R)-epoxide.
Gu Y, Xiao B, Wargo HL, Bucher MH, Singh SV, Ji X. Gu Y, et al. Biochemistry. 2003 Feb 4;42(4):917-21. doi: 10.1021/bi026778+. Biochemistry. 2003. PMID: 12549910
The crystal structure of mGSTA1-1 in complex with the GSH conjugate of (+)-anti-7,8-dihydroxy-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene (GSBpd) reveals that R216 and I221 in the last helix play important roles in catalysis [Gu, Y., Singh, S. V., and Ji, X. (2000) B …
The crystal structure of mGSTA1-1 in complex with the GSH conjugate of (+)-anti-7,8-dihydroxy-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene (GS …
Structure-Based Design of Anticancer Prodrug PABA/NO.
Ji X, Pal A, Kalathur R, Hu X, Gu Y, Saavedra JE, Buzard GS, Srinivasan A, Keefer LK, Singh SV. Ji X, et al. Among authors: gu y. Drug Des Devel Ther. 2008;2:123-130. doi: 10.2147/dddt.s3931. Drug Des Devel Ther. 2008. PMID: 19662104 Free PMC article.
Characterization of four orthologs of stringent starvation protein A.
Andrykovitch M, Routzahn KM, Li M, Gu Y, Waugh DS, Ji X. Andrykovitch M, et al. Among authors: gu y. Acta Crystallogr D Biol Crystallogr. 2003 May;59(Pt 5):881-6. doi: 10.1107/s0907444903005699. Epub 2003 Apr 25. Acta Crystallogr D Biol Crystallogr. 2003. PMID: 12777805
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