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Blockade of the interleukin (IL)-2/IL-2 receptor pathway with a monoclonal anti-IL-2 receptor antibody (BT563) does not prevent the development of acute heart allograft rejection in humans.
van Gelder T, Baan CC, Balk AH, Knoop CJ, Holweg CT, van der Meer P, Mochtar B, Zondervan PE, Niesters HG, Weimar W. van Gelder T, et al. Among authors: holweg ct. Transplantation. 1998 Feb 15;65(3):405-10. doi: 10.1097/00007890-199802150-00020. Transplantation. 1998. PMID: 9484761 Clinical Trial.
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