Kinch L - Search Results

1

Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote.

Zhao Z, Tuakli-Wosornu Y, Lagace TA, Kinch L, Grishin NV, Horton JD, Cohen JC, Hobbs HH. Zhao Z, et al. Among authors: kinch l. Am J Hum Genet. 2006 Sep;79(3):514-23. doi: 10.1086/507488. Epub 2006 Jul 18. Am J Hum Genet. 2006. PMID: 16909389 Free PMC article.

2

Acidic residues important for substrate binding and cofactor reactivity in eukaryotic ornithine decarboxylase identified by alanine scanning mutagenesis.

Osterman AL, Kinch LN, Grishin NV, Phillips MA. Osterman AL, et al. Among authors: kinch ln. J Biol Chem. 1995 May 19;270(20):11797-802. doi: 10.1074/jbc.270.20.11797. J Biol Chem. 1995. PMID: 7744828 Free article.

3

Formation of functional cross-species heterodimers of ornithine decarboxylase.

Osterman A, Grishin NV, Kinch LN, Phillips MA. Osterman A, et al. Among authors: kinch ln. Biochemistry. 1994 Nov 22;33(46):13662-7. doi: 10.1021/bi00250a016. Biochemistry. 1994. PMID: 7947774

4

Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer.

Wang Y, Kuan PJ, Xing C, Cronkhite JT, Torres F, Rosenblatt RL, DiMaio JM, Kinch LN, Grishin NV, Garcia CK. Wang Y, et al. Among authors: kinch ln. Am J Hum Genet. 2009 Jan;84(1):52-9. doi: 10.1016/j.ajhg.2008.11.010. Epub 2008 Dec 18. Am J Hum Genet. 2009. PMID: 19100526 Free PMC article.

5

A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis.

He S, McPhaul C, Li JZ, Garuti R, Kinch L, Grishin NV, Cohen JC, Hobbs HH. He S, et al. Among authors: kinch l. J Biol Chem. 2010 Feb 26;285(9):6706-15. doi: 10.1074/jbc.M109.064501. Epub 2009 Dec 23. J Biol Chem. 2010. PMID: 20034933 Free PMC article.

6

Sequences in the nonconsensus nucleotide-binding domain of ABCG5/ABCG8 required for sterol transport.

Wang J, Grishin N, Kinch L, Cohen JC, Hobbs HH, Xie XS. Wang J, et al. Among authors: kinch l. J Biol Chem. 2011 Mar 4;286(9):7308-14. doi: 10.1074/jbc.M110.210880. Epub 2011 Jan 5. J Biol Chem. 2011. PMID: 21209088 Free PMC article.

7

Crystal structure of the human sterol transporter ABCG5/ABCG8.

Lee JY, Kinch LN, Borek DM, Wang J, Wang J, Urbatsch IL, Xie XS, Grishin NV, Cohen JC, Otwinowski Z, Hobbs HH, Rosenbaum DM. Lee JY, et al. Among authors: kinch ln. Nature. 2016 May 26;533(7604):561-4. doi: 10.1038/nature17666. Epub 2016 May 4. Nature. 2016. PMID: 27144356 Free PMC article.

8

HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing.

Liu H, Liang C, Kollipara RK, Matsui M, Ke X, Jeong BC, Wang Z, Yoo KS, Yadav GP, Kinch LN, Grishin NV, Nam Y, Corey DR, Kittler R, Liu Q. Liu H, et al. Mol Cell. 2016 Aug 4;63(3):420-32. doi: 10.1016/j.molcel.2016.06.014. Epub 2016 Jul 14. Mol Cell. 2016. PMID: 27425409 Free PMC article.

9

The ubiquitin E3 ligase BFAR promotes degradation of PNPLA3.

Das A, Cheng H, Wang Y, Kinch LN, Liang G, Hong S, Hobbs HH, Cohen JC. Das A, et al. Among authors: kinch ln. Proc Natl Acad Sci U S A. 2024 Feb 6;121(6):e2312291121. doi: 10.1073/pnas.2312291121. Epub 2024 Jan 31. Proc Natl Acad Sci U S A. 2024. PMID: 38294943 Free PMC article.

10

Evolution of protein structures and functions.

Kinch LN, Grishin NV. Kinch LN, et al. Curr Opin Struct Biol. 2002 Jun;12(3):400-8. doi: 10.1016/s0959-440x(02)00338-x. Curr Opin Struct Biol. 2002. PMID: 12127461 Review.

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