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2-Aminoquinoline melanin-concentrating hormone (MCH)1R antagonists.
Jiang J, Hoang M, Young JR, Chaung D, Eid R, Turner C, Lin P, Tong X, Wang J, Tan C, Feighner S, Palyha O, Hreniuk DL, Pan J, Sailer AW, MacNeil DJ, Howard A, Shearman L, Stribling S, Camacho R, Strack A, Van der Ploeg LH, Goulet MT, DeVita RJ. Jiang J, et al. Among authors: hreniuk dl. Bioorg Med Chem Lett. 2006 Oct 15;16(20):5270-4. doi: 10.1016/j.bmcl.2006.08.006. Epub 2006 Aug 17. Bioorg Med Chem Lett. 2006. PMID: 16919456
Synthesis and biological evaluation in vitro of a selective, high potency peptide agonist of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1.
Bednarek MA, Tan C, Hreniuk DL, Palyha OC, MacNeil DJ, Van Der Ploeg LH, Howard AD, Feighner SD. Bednarek MA, et al. Among authors: hreniuk dl. J Biol Chem. 2002 Apr 19;277(16):13821-6. doi: 10.1074/jbc.M200563200. Epub 2002 Feb 11. J Biol Chem. 2002. PMID: 11839762 Free article.
Chronic MCH-1 receptor modulation alters appetite, body weight and adiposity in rats.
Shearman LP, Camacho RE, Sloan Stribling D, Zhou D, Bednarek MA, Hreniuk DL, Feighner SD, Tan CP, Howard AD, Van der Ploeg LH, MacIntyre DE, Hickey GJ, Strack AM. Shearman LP, et al. Among authors: hreniuk dl. Eur J Pharmacol. 2003 Aug 15;475(1-3):37-47. doi: 10.1016/s0014-2999(03)02146-0. Eur J Pharmacol. 2003. PMID: 12954357
4-Aminoquinoline melanin-concentrating hormone 1-receptor (MCH1R) antagonists.
Jiang J, Lin P, Hoang M, Chang L, Tan C, Feighner S, Palyha OC, Hreniuk DL, Pan J, Sailer AW, Morin NR, MacNeil DJ, Howard AD, Van der Ploeg LH, Goulet MT, DeVita RJ. Jiang J, et al. Among authors: hreniuk dl. Bioorg Med Chem Lett. 2006 Oct 15;16(20):5275-9. doi: 10.1016/j.bmcl.2006.08.008. Epub 2006 Aug 17. Bioorg Med Chem Lett. 2006. PMID: 16919453
Melanin-concentrating hormone receptor subtypes 1 and 2: species-specific gene expression.
Tan CP, Sano H, Iwaasa H, Pan J, Sailer AW, Hreniuk DL, Feighner SD, Palyha OC, Pong SS, Figueroa DJ, Austin CP, Jiang MM, Yu H, Ito J, Ito M, Ito M, Guan XM, MacNeil DJ, Kanatani A, Van der Ploeg LH, Howard AD. Tan CP, et al. Among authors: hreniuk dl. Genomics. 2002 Jun;79(6):785-92. doi: 10.1006/geno.2002.6771. Genomics. 2002. PMID: 12036292
Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R.
Sailer AW, Sano H, Zeng Z, McDonald TP, Pan J, Pong SS, Feighner SD, Tan CP, Fukami T, Iwaasa H, Hreniuk DL, Morin NR, Sadowski SJ, Ito M, Ito M, Bansal A, Ky B, Figueroa DJ, Jiang Q, Austin CP, MacNeil DJ, Ishihara A, Ihara M, Kanatani A, Van der Ploeg LH, Howard AD, Liu Q. Sailer AW, et al. Among authors: hreniuk dl. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7564-9. doi: 10.1073/pnas.121170598. Epub 2001 Jun 12. Proc Natl Acad Sci U S A. 2001. PMID: 11404457 Free PMC article.
Spiro(indoline-3,4'-piperidine) growth hormone secretagogues as ghrelin mimetics.
Palucki BL, Feighner SD, Pong S, McKee KK, Hreniuk DL, Tan C, Howard AD, Van der Ploeg LH, Patchett AA, Nargund RP. Palucki BL, et al. Among authors: hreniuk dl. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1955-7. doi: 10.1016/s0960-894x(01)00324-9. Bioorg Med Chem Lett. 2001. PMID: 11459669
46 results