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Genome-wide and fine-mapping linkage studies of type 2 diabetes and glucose traits in the Old Order Amish: evidence for a new diabetes locus on chromosome 14q11 and confirmation of a locus on chromosome 1q21-q24.
Hsueh WC, St Jean PL, Mitchell BD, Pollin TI, Knowler WC, Ehm MG, Bell CJ, Sakul H, Wagner MJ, Burns DK, Shuldiner AR. Hsueh WC, et al. Among authors: shuldiner ar. Diabetes. 2003 Feb;52(2):550-7. doi: 10.2337/diabetes.52.2.550. Diabetes. 2003. PMID: 12540634
Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q.
Zeggini E, Damcott CM, Hanson RL, Karim MA, Rayner NW, Groves CJ, Baier LJ, Hale TC, Hattersley AT, Hitman GA, Hunt SE, Knowler WC, Mitchell BD, Ng MC, O'Connell JR, Pollin TI, Vaxillaire M, Walker M, Wang X, Whittaker P, Xiang K, Jia W, Chan JC, Froguel P, Deloukas P, Shuldiner AR, Elbein SC, McCarthy MI; International Type 2 Diabetes 1q Consortium. Zeggini E, et al. Among authors: shuldiner ar. Diabetes. 2006 Sep;55(9):2541-8. doi: 10.2337/db06-0088. Diabetes. 2006. PMID: 16936202 Free article.
Variants in ARHGEF11, a candidate gene for the linkage to type 2 diabetes on chromosome 1q, are nominally associated with insulin resistance and type 2 diabetes in Pima Indians.
Ma L, Hanson RL, Que LN, Cali AM, Fu M, Mack JL, Infante AM, Kobes S; International Type 2 Diabetes 1q Consortium; Bogardus C, Shuldiner AR, Baier LJ. Ma L, et al. Among authors: shuldiner ar. Diabetes. 2007 May;56(5):1454-9. doi: 10.2337/db06-0640. Epub 2007 Feb 7. Diabetes. 2007. PMID: 17287471
545 results