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A dissipative pathway for the structural evolution of DNA fibres.
Rizzuto FJ, Platnich CM, Luo X, Shen Y, Dore MD, Lachance-Brais C, Guarné A, Cosa G, Sleiman HF. Rizzuto FJ, et al. Among authors: dore md. Nat Chem. 2021 Sep;13(9):843-849. doi: 10.1038/s41557-021-00751-w. Epub 2021 Aug 9. Nat Chem. 2021. PMID: 34373598
Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma.
Connors RV, Wang Z, Harrison M, Zhang A, Wanska M, Hiscock S, Fox B, Dore M, Labelle M, Sudom A, Johnstone S, Liu J, Walker NP, Chai A, Siegler K, Li Y, Coward P. Connors RV, et al. Among authors: dore m. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3550-4. doi: 10.1016/j.bmcl.2009.04.151. Epub 2009 May 9. Bioorg Med Chem Lett. 2009. PMID: 19464171
Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors.
Bagdanoff JT, Chen Z, Acker M, Chen YN, Chan H, Dore M, Firestone B, Fodor M, Fortanet J, Hentemann M, Kato M, Koenig R, LaBonte LR, Liu S, Mohseni M, Ntaganda R, Sarver P, Smith T, Sendzik M, Stams T, Spence S, Towler C, Wang H, Wang P, Williams SL, LaMarche MJ. Bagdanoff JT, et al. Among authors: dore m. J Med Chem. 2019 Feb 28;62(4):1781-1792. doi: 10.1021/acs.jmedchem.8b01725. Epub 2019 Feb 8. J Med Chem. 2019. PMID: 30688462
Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.
LaMarche MJ, Acker M, Argintaru A, Bauer D, Boisclair J, Chan H, Chen CH, Chen YN, Chen Z, Deng Z, Dore M, Dunstan D, Fan J, Fekkes P, Firestone B, Fodor M, Garcia-Fortanet J, Fortin PD, Fridrich C, Giraldes J, Glick M, Grunenfelder D, Hao HX, Hentemann M, Ho S, Jouk A, Kang ZB, Karki R, Kato M, Keen N, Koenig R, LaBonte LR, Larrow J, Liu G, Liu S, Majumdar D, Mathieu S, Meyer MJ, Mohseni M, Ntaganda R, Palermo M, Perez L, Pu M, Ramsey T, Reilly J, Sarver P, Sellers WR, Sendzik M, Shultz MD, Slisz J, Slocum K, Smith T, Spence S, Stams T, Straub C, Tamez V Jr, Toure BB, Towler C, Wang P, Wang H, Williams SL, Yang F, Yu B, Zhang JH, Zhu S. LaMarche MJ, et al. Among authors: dore m. J Med Chem. 2020 Nov 25;63(22):13578-13594. doi: 10.1021/acs.jmedchem.0c01170. Epub 2020 Sep 24. J Med Chem. 2020. PMID: 32910655
523 results