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Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema.
Brown SJ, Sandilands A, Zhao Y, Liao H, Relton CL, Meggitt SJ, Trembath RC, Barker JN, Reynolds NJ, Cordell HJ, McLean WH. Brown SJ, et al. Among authors: meggitt sj. J Invest Dermatol. 2008 Jun;128(6):1591-4. doi: 10.1038/sj.jid.5701206. Epub 2007 Dec 20. J Invest Dermatol. 2008. PMID: 18094728 Free article. No abstract available.
Azathioprine for atopic dermatitis.
Meggitt SJ, Reynolds NJ. Meggitt SJ, et al. Clin Exp Dermatol. 2001 Jul;26(5):369-75. doi: 10.1046/j.1365-2230.2001.00837.x. Clin Exp Dermatol. 2001. PMID: 11488818 Review.
Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk.
Weidinger S, Baurecht H, Wagenpfeil S, Henderson J, Novak N, Sandilands A, Chen H, Rodriguez E, O'Regan GM, Watson R, Liao H, Zhao Y, Barker JN, Allen M, Reynolds N, Meggitt S, Northstone K, Smith GD, Strobl C, Stahl C, Kneib T, Klopp N, Bieber T, Behrendt H, Palmer CN, Wichmann HE, Ring J, Illig T, McLean WH, Irvine AD. Weidinger S, et al. J Allergy Clin Immunol. 2008 Sep;122(3):560-8.e4. doi: 10.1016/j.jaci.2008.05.050. J Allergy Clin Immunol. 2008. PMID: 18774391
Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.
Saunders SP, Goh CS, Brown SJ, Palmer CN, Porter RM, Cole C, Campbell LE, Gierlinski M, Barton GJ, Schneider G, Balmain A, Prescott AR, Weidinger S, Baurecht H, Kabesch M, Gieger C, Lee YA, Tavendale R, Mukhopadhyay S, Turner SW, Madhok VB, Sullivan FM, Relton C, Burn J, Meggitt S, Smith CH, Allen MA, Barker JN, Reynolds NJ, Cordell HJ, Irvine AD, McLean WH, Sandilands A, Fallon PG. Saunders SP, et al. Among authors: meggitt s. J Allergy Clin Immunol. 2013 Nov;132(5):1121-9. doi: 10.1016/j.jaci.2013.08.046. Epub 2013 Sep 29. J Allergy Clin Immunol. 2013. PMID: 24084074 Free PMC article.
Translating translation into patient benefit for atopic eczema.
Reynolds NJ, Sinha A, Elias MS, Meggitt SJ. Reynolds NJ, et al. Among authors: meggitt sj. Br J Dermatol. 2016 Oct;175 Suppl 2(Suppl Suppl 2):8-12. doi: 10.1111/bjd.14909. Br J Dermatol. 2016. PMID: 27667309 Free PMC article. Review.
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
Navarini AA, Simpson MA, Weale M, Knight J, Carlavan I, Reiniche P, Burden DA, Layton A, Bataille V, Allen M, Pleass R, Pink A, Creamer D, English J, Munn S, Walton S; Acne Genetic Study Group; Willis C, Déret S, Voegel JJ, Spector T, Smith CH, Trembath RC, Barker JN. Navarini AA, et al. Nat Commun. 2014 Jun 13;5:4020. doi: 10.1038/ncomms5020. Nat Commun. 2014. PMID: 24927181 Free article.
39 results