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Quantitative determination of zebularine (NSC 309132), a DNA methyltransferase inhibitor, and three metabolites in murine plasma by high-performance liquid chromatography coupled with on-line radioactivity detection.
Beumer JH, Joseph E, Egorin MJ, Covey JM, Eiseman JL. Beumer JH, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Feb 2;831(1-2):147-55. doi: 10.1016/j.jchromb.2005.11.048. Epub 2005 Dec 20. J Chromatogr B Analyt Technol Biomed Life Sci. 2006. PMID: 16364698
Plasma pharmacokinetics and oral bioavailability of the 3,4,5,6-tetrahydrouridine (THU) prodrug, triacetyl-THU (taTHU), in mice.
Beumer JH, Eiseman JL, Gilbert JA, Holleran JL, Yellow-Duke AE, Clausen DM, D'Argenio DZ, Ames MM, Hershberger PA, Parise RA, Bai L, Covey JM, Egorin MJ. Beumer JH, et al. Cancer Chemother Pharmacol. 2011 Feb;67(2):421-30. doi: 10.1007/s00280-010-1337-6. Epub 2010 May 5. Cancer Chemother Pharmacol. 2011. PMID: 20443002 Free PMC article.
A liquid chromatography-electrospray ionization tandem mass spectrometric assay for quantitation of the histone deacetylase inhibitor, vorinostat (suberoylanilide hydroxamicacid, SAHA), and its metabolites in human serum.
Parise RA, Holleran JL, Beumer JH, Ramalingam S, Egorin MJ. Parise RA, et al. Among authors: beumer jh. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Aug 18;840(2):108-15. doi: 10.1016/j.jchromb.2006.04.044. Epub 2006 May 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2006. PMID: 16725386
201 results