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Identification of TUB as a novel candidate gene influencing body weight in humans.
Shiri-Sverdlov R, Custers A, van Vliet-Ostaptchouk JV, van Gorp PJ, Lindsey PJ, van Tilburg JH, Zhernakova S, Feskens EJ, van der A DL, Dollé ME, van Haeften TW, Koeleman BP, Hofker MH, Wijmenga C. Shiri-Sverdlov R, et al. Diabetes. 2006 Feb;55(2):385-9. doi: 10.2337/diabetes.55.02.06.db05-0997. Diabetes. 2006. PMID: 16443771 Free article.
Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians.
Meex SJ, van Greevenbroek MM, Ayoubi TA, Vlietinck R, van Vliet-Ostaptchouk JV, Hofker MH, Vermeulen VM, Schalkwijk CG, Feskens EJ, Boer JM, Stehouwer CD, van der Kallen CJ, de Bruin TW. Meex SJ, et al. J Clin Endocrinol Metab. 2007 Jul;92(7):2720-5. doi: 10.1210/jc.2006-2280. Epub 2007 Apr 17. J Clin Endocrinol Metab. 2007. PMID: 17440018 Free article.
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes.
Steinthorsdottir V, Thorleifsson G, Reynisdottir I, Benediktsson R, Jonsdottir T, Walters GB, Styrkarsdottir U, Gretarsdottir S, Emilsson V, Ghosh S, Baker A, Snorradottir S, Bjarnason H, Ng MC, Hansen T, Bagger Y, Wilensky RL, Reilly MP, Adeyemo A, Chen Y, Zhou J, Gudnason V, Chen G, Huang H, Lashley K, Doumatey A, So WY, Ma RC, Andersen G, Borch-Johnsen K, Jorgensen T, van Vliet-Ostaptchouk JV, Hofker MH, Wijmenga C, Christiansen C, Rader DJ, Rotimi C, Gurney M, Chan JC, Pedersen O, Sigurdsson G, Gulcher JR, Thorsteinsdottir U, Kong A, Stefansson K. Steinthorsdottir V, et al. Nat Genet. 2007 Jun;39(6):770-5. doi: 10.1038/ng2043. Epub 2007 Apr 26. Nat Genet. 2007. PMID: 17460697 Free article. Clinical Trial.
TUB is a candidate gene for late-onset obesity in women.
Snieder H, Wang X, Shiri-Sverdlov R, van Vliet-Ostaptchouk JV, Hofker MH, Perks U, Spector TD, O'Dell SD. Snieder H, et al. Diabetologia. 2008 Jan;51(1):54-61. doi: 10.1007/s00125-007-0851-5. Epub 2007 Oct 23. Diabetologia. 2008. PMID: 17955208
Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study.
Reiling E, van Vliet-Ostaptchouk JV, van 't Riet E, van Haeften TW, Arp PA, Hansen T, Kremer D, Groenewoud MJ, van Hove EC, Romijn JA, Smit JW, Nijpels G, Heine RJ, Uitterlinden AG, Pedersen O, Slagboom PE, Maassen JA, Hofker MH, 't Hart LM, Dekker JM. Reiling E, et al. Eur J Hum Genet. 2009 Aug;17(8):1056-62. doi: 10.1038/ejhg.2009.4. Epub 2009 Feb 11. Eur J Hum Genet. 2009. PMID: 19209188 Free PMC article.
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