The Paneth cell alpha-defensin deficiency of ileal Crohn's disease is linked to Wnt/Tcf-4.
Wehkamp J, Wang G, Kübler I, Nuding S, Gregorieff A, Schnabel A, Kays RJ, Fellermann K, Burk O, Schwab M, Clevers H, Bevins CL, Stange EF.
Wehkamp J, et al.
J Immunol. 2007 Sep 1;179(5):3109-18. doi: 10.4049/jimmunol.179.5.3109.
J Immunol. 2007.
PMID: 17709525