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Candidate inhibitors of porcine complement.
Thorgersen EB, Ghebremariam YT, Thurman JM, Fung M, Nielsen EW, Holers VM, Kotwal GJ, Mollnes TE. Thorgersen EB, et al. Among authors: ghebremariam yt. Mol Immunol. 2007 Mar;44(8):1827-34. doi: 10.1016/j.molimm.2006.10.004. Epub 2006 Nov 15. Mol Immunol. 2007. PMID: 17109963
Humanized recombinant vaccinia virus complement control protein (hrVCP) with three amino acid changes, H98Y, E102K, and E120K creating an additional putative heparin binding site, is 100-fold more active than rVCP in blocking both classical and alternative complement pathways.
Ghebremariam YT, Odunuga OO, Janse K, Kotwal GJ. Ghebremariam YT, et al. Ann N Y Acad Sci. 2005 Nov;1056:113-22. doi: 10.1196/annals.1352.024. Ann N Y Acad Sci. 2005. PMID: 16387681
Anti-HIV, anti-poxvirus, and anti-SARS activity of a nontoxic, acidic plant extract from the Trifollium species Secomet-V/anti-vac suggests that it contains a novel broad-spectrum antiviral.
Kotwal GJ, Kaczmarek JN, Leivers S, Ghebremariam YT, Kulkarni AP, Bauer G, De Beer C, Preiser W, Mohamed AR. Kotwal GJ, et al. Among authors: ghebremariam yt. Ann N Y Acad Sci. 2005 Nov;1056(1):293-302. doi: 10.1196/annals.1352.014. Ann N Y Acad Sci. 2005. PMID: 16387696 Free PMC article.
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