Westwick JK - Search Results

1

Fluorescent protein-based cellular assays analyzed by laser-scanning microplate cytometry in 1536-well plate format.

Auld DS, Johnson RL, Zhang YQ, Veith H, Jadhav A, Yasgar A, Simeonov A, Zheng W, Martinez ED, Westwick JK, Austin CP, Inglese J. Auld DS, et al. Among authors: westwick jk. Methods Enzymol. 2006;414:566-89. doi: 10.1016/S0076-6879(06)14029-X. Methods Enzymol. 2006. PMID: 17110211

2

Protein-fragment complementation assays (PCA) in small GTPase research and drug discovery.

Westwick JK, Michnick SW. Westwick JK, et al. Methods Enzymol. 2006;407:388-401. doi: 10.1016/S0076-6879(05)07032-1. Methods Enzymol. 2006. PMID: 16757340

3

Functional proteomics analysis of GTPase signaling networks.

Alton G, Cox AD, Toussaint LG 3rd, Westwick JK. Alton G, et al. Among authors: westwick jk. Methods Enzymol. 2001;332:300-16. doi: 10.1016/s0076-6879(01)32211-5. Methods Enzymol. 2001. PMID: 11305106 No abstract available.

4

Chemical genetic strategies to delineate MAP kinase signaling pathways using protein-fragment complementation assays (PCA).

Michnick SW, MacDonald ML, Westwick JK. Michnick SW, et al. Among authors: westwick jk. Methods. 2006 Nov;40(3):287-93. doi: 10.1016/j.ymeth.2006.07.016. Methods. 2006. PMID: 17071407 Review.

5

Identifying off-target effects and hidden phenotypes of drugs in human cells.

MacDonald ML, Lamerdin J, Owens S, Keon BH, Bilter GK, Shang Z, Huang Z, Yu H, Dias J, Minami T, Michnick SW, Westwick JK. MacDonald ML, et al. Among authors: westwick jk. Nat Chem Biol. 2006 Jun;2(6):329-37. doi: 10.1038/nchembio790. Epub 2006 May 7. Nat Chem Biol. 2006. PMID: 16680159

6

Measuring drug action in the cellular context using protein-fragment complementation assays.

Yu H, West M, Keon BH, Bilter GK, Owens S, Lamerdin J, Westwick JK. Yu H, et al. Among authors: westwick jk. Assay Drug Dev Technol. 2003 Dec;1(6):811-22. doi: 10.1089/154065803772613444. Assay Drug Dev Technol. 2003. PMID: 15090227

7

Ras-mediated transcription activation: analysis by transient cotransfection assays.

Hauser CA, Westwick JK, Quilliam LA. Hauser CA, et al. Among authors: westwick jk. Methods Enzymol. 1995;255:412-26. doi: 10.1016/s0076-6879(95)55043-7. Methods Enzymol. 1995. PMID: 8524127 No abstract available.

8

The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation.

Cox AD, Garcia AM, Westwick JK, Kowalczyk JJ, Lewis MD, Brenner DA, Der CJ. Cox AD, et al. Among authors: westwick jk. J Biol Chem. 1994 Jul 29;269(30):19203-6. J Biol Chem. 1994. PMID: 8034681 Free article.

9

Therapeutic modulation of inflammatory gene transcription by kinase inhibitors.

Alton G, Schwamborn K, Satoh Y, Westwick JK. Alton G, et al. Among authors: westwick jk. Expert Opin Biol Ther. 2002 Aug;2(6):621-32. doi: 10.1517/14712598.2.6.621. Expert Opin Biol Ther. 2002. PMID: 12171506 Review.

10

Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases.

Westwick JK, Cox AD, Der CJ, Cobb MH, Hibi M, Karin M, Brenner DA. Westwick JK, et al. Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):6030-4. doi: 10.1073/pnas.91.13.6030. Proc Natl Acad Sci U S A. 1994. PMID: 8016110 Free PMC article.

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