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Phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 (P-Rex-1), a guanine nucleotide exchange factor for Rac, mediates angiogenic responses to stromal cell-derived factor-1/chemokine stromal cell derived factor-1 (SDF-1/CXCL-12) linked to Rac activation, endothelial cell migration, and in vitro angiogenesis.
Carretero-Ortega J, Walsh CT, Hernández-García R, Reyes-Cruz G, Brown JH, Vázquez-Prado J. Carretero-Ortega J, et al. Among authors: walsh ct. Mol Pharmacol. 2010 Mar;77(3):435-42. doi: 10.1124/mol.109.060400. Epub 2009 Dec 17. Mol Pharmacol. 2010. PMID: 20018810 Free PMC article.
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