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Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma.
Francis LK, Alsayed Y, Leleu X, Jia X, Singha UK, Anderson J, Timm M, Ngo H, Lu G, Huston A, Ehrlich LA, Dimmock E, Lentzsch S, Hideshima T, Roodman GD, Anderson KC, Ghobrial IM. Francis LK, et al. Among authors: roodman gd. Clin Cancer Res. 2006 Nov 15;12(22):6826-35. doi: 10.1158/1078-0432.CCR-06-1331. Clin Cancer Res. 2006. PMID: 17121904
Chemokines in multiple myeloma.
Aggarwal R, Ghobrial IM, Roodman GD. Aggarwal R, et al. Among authors: roodman gd. Exp Hematol. 2006 Oct;34(10):1289-95. doi: 10.1016/j.exphem.2006.06.017. Exp Hematol. 2006. PMID: 16982321 Free PMC article. Review.
Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma.
Alsayed Y, Ngo H, Runnels J, Leleu X, Singha UK, Pitsillides CM, Spencer JA, Kimlinger T, Ghobrial JM, Jia X, Lu G, Timm M, Kumar A, Côté D, Veilleux I, Hedin KE, Roodman GD, Witzig TE, Kung AL, Hideshima T, Anderson KC, Lin CP, Ghobrial IM. Alsayed Y, et al. Among authors: roodman gd. Blood. 2007 Apr 1;109(7):2708-17. doi: 10.1182/blood-2006-07-035857. Blood. 2007. PMID: 17119115 Free PMC article.
Pathophysiology of multiple myeloma bone disease.
Lentzsch S, Ehrlich LA, Roodman GD. Lentzsch S, et al. Among authors: roodman gd. Hematol Oncol Clin North Am. 2007 Dec;21(6):1035-49, viii. doi: 10.1016/j.hoc.2007.08.009. Hematol Oncol Clin North Am. 2007. PMID: 17996587 Review.
Annexin II stimulates RANKL expression through MAPK.
Li F, Chung H, Reddy SV, Lu G, Kurihara N, Zhao AZ, Roodman GD. Li F, et al. Among authors: roodman gd. J Bone Miner Res. 2005 Jul;20(7):1161-7. doi: 10.1359/JBMR.050207. Epub 2005 Feb 14. J Bone Miner Res. 2005. PMID: 15940368 Free article.
296 results