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Page 1
T1DBase: integration and presentation of complex data for type 1 diabetes research.
Hulbert EM, Smink LJ, Adlem EC, Allen JE, Burdick DB, Burren OS, Cassen VM, Cavnor CC, Dolman GE, Flamez D, Friery KF, Healy BC, Killcoyne SA, Kutlu B, Schuilenburg H, Walker NM, Mychaleckyj J, Eizirik DL, Wicker LS, Todd JA, Goodman N. Hulbert EM, et al. Among authors: smink lj. Nucleic Acids Res. 2007 Jan;35(Database issue):D742-6. doi: 10.1093/nar/gkl933. Epub 2006 Dec 14. Nucleic Acids Res. 2007. PMID: 17169983 Free PMC article.
T1DBase, a community web-based resource for type 1 diabetes research.
Smink LJ, Helton EM, Healy BC, Cavnor CC, Lam AC, Flamez D, Burren OS, Wang Y, Dolman GE, Burdick DB, Everett VH, Glusman G, Laneri D, Rowen L, Schuilenburg H, Walker NM, Mychaleckyj J, Wicker LS, Eizirik DL, Todd JA, Goodman N. Smink LJ, et al. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D544-9. doi: 10.1093/nar/gki095. Nucleic Acids Res. 2005. PMID: 15608258 Free PMC article.
Development of an integrated genome informatics, data management and workflow infrastructure: a toolbox for the study of complex disease genetics.
Burren OS, Healy BC, Lam AC, Schuilenburg H, Dolman GE, Everett VH, Laneri D, Nutland S, Rance HE, Payne F, Smyth D, Lowe C, Barratt BJ, Twells RC, Rainbow DB, Wicker LS, Todd JA, Walker NM, Smink LJ. Burren OS, et al. Among authors: smink lj. Hum Genomics. 2004 Jan;1(2):98-109. doi: 10.1186/1479-7364-1-2-98. Hum Genomics. 2004. PMID: 15601538 Free PMC article.
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.
Todd JA, Walker NM, Cooper JD, Smyth DJ, Downes K, Plagnol V, Bailey R, Nejentsev S, Field SF, Payne F, Lowe CE, Szeszko JS, Hafler JP, Zeitels L, Yang JH, Vella A, Nutland S, Stevens HE, Schuilenburg H, Coleman G, Maisuria M, Meadows W, Smink LJ, Healy B, Burren OS, Lam AA, Ovington NR, Allen J, Adlem E, Leung HT, Wallace C, Howson JM, Guja C, Ionescu-Tîrgovişte C; Genetics of Type 1 Diabetes in Finland; Simmonds MJ, Heward JM, Gough SC; Wellcome Trust Case Control Consortium; Dunger DB, Wicker LS, Clayton DG. Todd JA, et al. Among authors: smink lj. Nat Genet. 2007 Jul;39(7):857-64. doi: 10.1038/ng2068. Epub 2007 Jun 6. Nat Genet. 2007. PMID: 17554260 Free PMC article.
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.
Onengut-Gumuscu S, Chen WM, Burren O, Cooper NJ, Quinlan AR, Mychaleckyj JC, Farber E, Bonnie JK, Szpak M, Schofield E, Achuthan P, Guo H, Fortune MD, Stevens H, Walker NM, Ward LD, Kundaje A, Kellis M, Daly MJ, Barrett JC, Cooper JD, Deloukas P; Type 1 Diabetes Genetics Consortium; Todd JA, Wallace C, Concannon P, Rich SS. Onengut-Gumuscu S, et al. Nat Genet. 2015 Apr;47(4):381-6. doi: 10.1038/ng.3245. Epub 2015 Mar 9. Nat Genet. 2015. PMID: 25751624 Free PMC article.
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
Barrett JC, Clayton DG, Concannon P, Akolkar B, Cooper JD, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Plagnol V, Pociot F, Schuilenburg H, Smyth DJ, Stevens H, Todd JA, Walker NM, Rich SS; Type 1 Diabetes Genetics Consortium. Barrett JC, et al. Nat Genet. 2009 Jun;41(6):703-7. doi: 10.1038/ng.381. Epub 2009 May 10. Nat Genet. 2009. PMID: 19430480 Free PMC article.
Discovery, linkage disequilibrium and association analyses of polymorphisms of the immune complement inhibitor, decay-accelerating factor gene (DAF/CD55) in type 1 diabetes.
Taniguchi H, Lowe CE, Cooper JD, Smyth DJ, Bailey R, Nutland S, Healy BC, Lam AC, Burren O, Walker NM, Smink LJ, Wicker LS, Todd JA. Taniguchi H, et al. Among authors: smink lj. BMC Genet. 2006 Apr 20;7:22. doi: 10.1186/1471-2156-7-22. BMC Genet. 2006. PMID: 16626483 Free PMC article.
Interaction analysis of the CBLB and CTLA4 genes in type 1 diabetes.
Payne F, Cooper JD, Walker NM, Lam AC, Smink LJ, Nutland S, Stevens HE, Hutchings J, Todd JA. Payne F, et al. Among authors: smink lj. J Leukoc Biol. 2007 Mar;81(3):581-3. doi: 10.1189/jlb.0906577. Epub 2007 Jan 5. J Leukoc Biol. 2007. PMID: 17209142
Type 1 diabetes genes and pathways shared by humans and NOD mice.
Wicker LS, Clark J, Fraser HI, Garner VE, Gonzalez-Munoz A, Healy B, Howlett S, Hunter K, Rainbow D, Rosa RL, Smink LJ, Todd JA, Peterson LB. Wicker LS, et al. Among authors: smink lj. J Autoimmun. 2005;25 Suppl:29-33. doi: 10.1016/j.jaut.2005.09.009. Epub 2005 Oct 28. J Autoimmun. 2005. PMID: 16257508 Review.
40 results