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Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity.
Chao EY, Caravella JA, Watson MA, Campobasso N, Ghisletti S, Billin AN, Galardi C, Wang P, Laffitte BA, Iannone MA, Goodwin BJ, Nichols JA, Parks DJ, Stewart E, Wiethe RW, Williams SP, Smallwood A, Pearce KH, Glass CK, Willson TM, Zuercher WJ, Collins JL. Chao EY, et al. Among authors: willson tm. J Med Chem. 2008 Sep 25;51(18):5758-65. doi: 10.1021/jm800612u. J Med Chem. 2008. PMID: 18800767
Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.
Krylova IN, Sablin EP, Moore J, Xu RX, Waitt GM, MacKay JA, Juzumiene D, Bynum JM, Madauss K, Montana V, Lebedeva L, Suzawa M, Williams JD, Williams SP, Guy RK, Thornton JW, Fletterick RJ, Willson TM, Ingraham HA. Krylova IN, et al. Among authors: willson tm. Cell. 2005 Feb 11;120(3):343-55. doi: 10.1016/j.cell.2005.01.024. Cell. 2005. PMID: 15707893 Free article.
The effect of LXR activators on AP-1 proteins in keratinocytes.
Schmuth M, Elias PM, Hanley K, Lau P, Moser A, Willson TM, Bikle DD, Feingold KR. Schmuth M, et al. Among authors: willson tm. J Invest Dermatol. 2004 Jul;123(1):41-8. doi: 10.1111/j.0022-202X.2004.22707.x. J Invest Dermatol. 2004. PMID: 15191540 Free article.
225 results