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AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.
Batchelor TT, Sorensen AG, di Tomaso E, Zhang WT, Duda DG, Cohen KS, Kozak KR, Cahill DP, Chen PJ, Zhu M, Ancukiewicz M, Mrugala MM, Plotkin S, Drappatz J, Louis DN, Ivy P, Scadden DT, Benner T, Loeffler JS, Wen PY, Jain RK. Batchelor TT, et al. Among authors: zhang wt. Cancer Cell. 2007 Jan;11(1):83-95. doi: 10.1016/j.ccr.2006.11.021. Cancer Cell. 2007. PMID: 17222792 Free PMC article. Clinical Trial.
A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients.
Sorensen AG, Batchelor TT, Zhang WT, Chen PJ, Yeo P, Wang M, Jennings D, Wen PY, Lahdenranta J, Ancukiewicz M, di Tomaso E, Duda DG, Jain RK. Sorensen AG, et al. Among authors: zhang wt. Cancer Res. 2009 Jul 1;69(13):5296-300. doi: 10.1158/0008-5472.CAN-09-0814. Epub 2009 Jun 23. Cancer Res. 2009. PMID: 19549889 Free PMC article.
Response criteria for glioma.
Sorensen AG, Batchelor TT, Wen PY, Zhang WT, Jain RK. Sorensen AG, et al. Among authors: zhang wt. Nat Clin Pract Oncol. 2008 Nov;5(11):634-44. doi: 10.1038/ncponc1204. Epub 2008 Aug 19. Nat Clin Pract Oncol. 2008. PMID: 18711427 Free PMC article. Review.
282 results