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Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization.
Combs TP, Wagner JA, Berger J, Doebber T, Wang WJ, Zhang BB, Tanen M, Berg AH, O'Rahilly S, Savage DB, Chatterjee K, Weiss S, Larson PJ, Gottesdiener KM, Gertz BJ, Charron MJ, Scherer PE, Moller DE. Combs TP, et al. Among authors: scherer pe. Endocrinology. 2002 Mar;143(3):998-1007. doi: 10.1210/endo.143.3.8662. Endocrinology. 2002. PMID: 11861525 Clinical Trial.
A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity.
Combs TP, Pajvani UB, Berg AH, Lin Y, Jelicks LA, Laplante M, Nawrocki AR, Rajala MW, Parlow AF, Cheeseboro L, Ding YY, Russell RG, Lindemann D, Hartley A, Baker GR, Obici S, Deshaies Y, Ludgate M, Rossetti L, Scherer PE. Combs TP, et al. Among authors: scherer pe. Endocrinology. 2004 Jan;145(1):367-83. doi: 10.1210/en.2003-1068. Epub 2003 Oct 23. Endocrinology. 2004. PMID: 14576179
Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity.
Pajvani UB, Hawkins M, Combs TP, Rajala MW, Doebber T, Berger JP, Wagner JA, Wu M, Knopps A, Xiang AH, Utzschneider KM, Kahn SE, Olefsky JM, Buchanan TA, Scherer PE. Pajvani UB, et al. Among authors: scherer pe. J Biol Chem. 2004 Mar 26;279(13):12152-62. doi: 10.1074/jbc.M311113200. Epub 2003 Dec 29. J Biol Chem. 2004. PMID: 14699128 Free article.
The adipocyte as an important target cell for Trypanosoma cruzi infection.
Combs TP, Nagajyothi, Mukherjee S, de Almeida CJ, Jelicks LA, Schubert W, Lin Y, Jayabalan DS, Zhao D, Braunstein VL, Landskroner-Eiger S, Cordero A, Factor SM, Weiss LM, Lisanti MP, Tanowitz HB, Scherer PE. Combs TP, et al. Among authors: scherer pe. J Biol Chem. 2005 Jun 24;280(25):24085-94. doi: 10.1074/jbc.M412802200. Epub 2005 Apr 18. J Biol Chem. 2005. PMID: 15843370 Free article.
Proangiogenic contribution of adiponectin toward mammary tumor growth in vivo.
Landskroner-Eiger S, Qian B, Muise ES, Nawrocki AR, Berger JP, Fine EJ, Koba W, Deng Y, Pollard JW, Scherer PE. Landskroner-Eiger S, et al. Among authors: scherer pe. Clin Cancer Res. 2009 May 15;15(10):3265-76. doi: 10.1158/1078-0432.CCR-08-2649. Epub 2009 May 15. Clin Cancer Res. 2009. PMID: 19447867 Free PMC article.
C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists.
Vernochet C, Peres SB, Davis KE, McDonald ME, Qiang L, Wang H, Scherer PE, Farmer SR. Vernochet C, et al. Among authors: scherer pe. Mol Cell Biol. 2009 Sep;29(17):4714-28. doi: 10.1128/MCB.01899-08. Epub 2009 Jun 29. Mol Cell Biol. 2009. PMID: 19564408 Free PMC article.
516 results