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A prime-boost strategy using virus-like particles pseudotyped for HCV proteins triggers broadly neutralizing antibodies in macaques.
Garrone P, Fluckiger AC, Mangeot PE, Gauthier E, Dupeyrot-Lacas P, Mancip J, Cangialosi A, Du Chéné I, LeGrand R, Mangeot I, Lavillette D, Bellier B, Cosset FL, Tangy F, Klatzmann D, Dalba C. Garrone P, et al. Among authors: dalba c. Sci Transl Med. 2011 Aug 3;3(94):94ra71. doi: 10.1126/scitranslmed.3002330. Sci Transl Med. 2011. PMID: 21813755
Down-regulation of CD81 in human cells producing HCV-E1/E2 retroVLPs.
Rodrigues AF, Guerreiro MR, Castro R, Tomás HA, Dalba C, Klatzmann D, Alves PM, Carrondo MJ, Coroadinha AS. Rodrigues AF, et al. Among authors: dalba c. BMC Proc. 2011 Nov 22;5 Suppl 8(Suppl 8):P72. doi: 10.1186/1753-6561-5-S8-P72. eCollection 2011. BMC Proc. 2011. PMID: 22373065 Free PMC article. No abstract available.
Enveloped virus-like particle expression of human cytomegalovirus glycoprotein B antigen induces antibodies with potent and broad neutralizing activity.
Kirchmeier M, Fluckiger AC, Soare C, Bozic J, Ontsouka B, Ahmed T, Diress A, Pereira L, Schödel F, Plotkin S, Dalba C, Klatzmann D, Anderson DE. Kirchmeier M, et al. Among authors: dalba c. Clin Vaccine Immunol. 2014 Feb;21(2):174-80. doi: 10.1128/CVI.00662-13. Epub 2013 Dec 11. Clin Vaccine Immunol. 2014. PMID: 24334684 Free PMC article.