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Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome.
Wang JC, Hinrichs AL, Stock H, Budde J, Allen R, Bertelsen S, Kwon JM, Wu W, Dick DM, Rice J, Jones K, Nurnberger JI Jr, Tischfield J, Porjesz B, Edenberg HJ, Hesselbrock V, Crowe R, Schuckit M, Begleiter H, Reich T, Goate AM, Bierut LJ. Wang JC, et al. Hum Mol Genet. 2004 Sep 1;13(17):1903-11. doi: 10.1093/hmg/ddh194. Epub 2004 Jun 30. Hum Mol Genet. 2004. PMID: 15229186
Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence.
Hinrichs AL, Wang JC, Bufe B, Kwon JM, Budde J, Allen R, Bertelsen S, Evans W, Dick D, Rice J, Foroud T, Nurnberger J, Tischfield JA, Kuperman S, Crowe R, Hesselbrock V, Schuckit M, Almasy L, Porjesz B, Edenberg HJ, Begleiter H, Meyerhof W, Bierut LJ, Goate AM. Hinrichs AL, et al. Among authors: wang jc. Am J Hum Genet. 2006 Jan;78(1):103-11. doi: 10.1086/499253. Epub 2005 Nov 21. Am J Hum Genet. 2006. PMID: 16385453 Free PMC article.
Alcohol dependence with comorbid drug dependence: genetic and phenotypic associations suggest a more severe form of the disorder with stronger genetic contribution to risk.
Dick DM, Agrawal A, Wang JC, Hinrichs A, Bertelsen S, Bucholz KK, Schuckit M, Kramer J, Nurnberger J Jr, Tischfield J, Edenberg HJ, Goate A, Bierut LJ. Dick DM, et al. Among authors: wang jc. Addiction. 2007 Jul;102(7):1131-9. doi: 10.1111/j.1360-0443.2007.01871.x. Addiction. 2007. PMID: 17567401
Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1.
Dick DM, Wang JC, Plunkett J, Aliev F, Hinrichs A, Bertelsen S, Budde JP, Goldstein EL, Kaplan D, Edenberg HJ, Nurnberger J Jr, Hesselbrock V, Schuckit M, Kuperman S, Tischfield J, Porjesz B, Begleiter H, Bierut LJ, Goate A. Dick DM, et al. Among authors: wang jc. Alcohol Clin Exp Res. 2007 Oct;31(10):1645-53. doi: 10.1111/j.1530-0277.2007.00470.x. Alcohol Clin Exp Res. 2007. PMID: 17850642
A Systematic single nucleotide polymorphism screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9.
Dick DM, Aliev F, Wang JC, Saccone S, Hinrichs A, Bertelsen S, Budde J, Saccone N, Foroud T, Nurnberger J Jr, Xuei X, Conneally PM, Schuckit M, Almasy L, Crowe R, Kuperman S, Kramer J, Tischfield JA, Hesselbrock V, Edenberg HJ, Porjesz B, Rice JP, Bierut L, Goate A. Dick DM, et al. Among authors: wang jc. Biol Psychiatry. 2008 Jun 1;63(11):1047-53. doi: 10.1016/j.biopsych.2007.11.005. Epub 2007 Dec 27. Biol Psychiatry. 2008. PMID: 18163977 Free PMC article.
Variants in nicotinic receptors and risk for nicotine dependence.
Bierut LJ, Stitzel JA, Wang JC, Hinrichs AL, Grucza RA, Xuei X, Saccone NL, Saccone SF, Bertelsen S, Fox L, Horton WJ, Breslau N, Budde J, Cloninger CR, Dick DM, Foroud T, Hatsukami D, Hesselbrock V, Johnson EO, Kramer J, Kuperman S, Madden PA, Mayo K, Nurnberger J Jr, Pomerleau O, Porjesz B, Reyes O, Schuckit M, Swan G, Tischfield JA, Edenberg HJ, Rice JP, Goate AM. Bierut LJ, et al. Among authors: wang jc. Am J Psychiatry. 2008 Sep;165(9):1163-71. doi: 10.1176/appi.ajp.2008.07111711. Epub 2008 Jun 2. Am J Psychiatry. 2008. PMID: 18519524 Free PMC article.
The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
Saccone NL, Wang JC, Breslau N, Johnson EO, Hatsukami D, Saccone SF, Grucza RA, Sun L, Duan W, Budde J, Culverhouse RC, Fox L, Hinrichs AL, Steinbach JH, Wu M, Rice JP, Goate AM, Bierut LJ. Saccone NL, et al. Among authors: wang jc. Cancer Res. 2009 Sep 1;69(17):6848-56. doi: 10.1158/0008-5472.CAN-09-0786. Epub 2009 Aug 25. Cancer Res. 2009. PMID: 19706762 Free PMC article.
A genome-wide association study of alcohol dependence.
Bierut LJ, Agrawal A, Bucholz KK, Doheny KF, Laurie C, Pugh E, Fisher S, Fox L, Howells W, Bertelsen S, Hinrichs AL, Almasy L, Breslau N, Culverhouse RC, Dick DM, Edenberg HJ, Foroud T, Grucza RA, Hatsukami D, Hesselbrock V, Johnson EO, Kramer J, Krueger RF, Kuperman S, Lynskey M, Mann K, Neuman RJ, Nöthen MM, Nurnberger JI Jr, Porjesz B, Ridinger M, Saccone NL, Saccone SF, Schuckit MA, Tischfield JA, Wang JC, Rietschel M, Goate AM, Rice JP; Gene, Environment Association Studies Consortium. Bierut LJ, et al. Among authors: wang jc. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5082-7. doi: 10.1073/pnas.0911109107. Epub 2010 Mar 2. Proc Natl Acad Sci U S A. 2010. PMID: 20202923 Free PMC article.
2,970 results