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Page 1
Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8.
Jenkins TJ, Guan B, Dai M, Li G, Lightburn TE, Huang S, Freeze BS, Burdi DF, Jacutin-Porte S, Bennett R, Chen W, Minor C, Ghosh S, Blackburn C, Gigstad KM, Jones M, Kolbeck R, Yin W, Smith S, Cardillo D, Ocain TD, Harriman GC. Jenkins TJ, et al. Among authors: kolbeck r. J Med Chem. 2007 Feb 8;50(3):566-84. doi: 10.1021/jm061118e. J Med Chem. 2007. PMID: 17266208
Design, synthesis, and progress toward optimization of potent small molecule antagonists of CC chemokine receptor 8 (CCR8).
Ghosh S, Elder A, Guo J, Mani U, Patane M, Carson K, Ye Q, Bennett R, Chi S, Jenkins T, Guan B, Kolbeck R, Smith S, Zhang C, LaRosa G, Jaffee B, Yang H, Eddy P, Lu C, Uttamsingh V, Horlick R, Harriman G, Flynn D. Ghosh S, et al. Among authors: kolbeck r. J Med Chem. 2006 May 4;49(9):2669-72. doi: 10.1021/jm050965z. J Med Chem. 2006. PMID: 16640325
Coordinated involvement of mast cells and T cells in allergic mucosal inflammation: critical role of the CC chemokine ligand 1:CCR8 axis.
Gonzalo JA, Qiu Y, Lora JM, Al-Garawi A, Villeval JL, Boyce JA, Martinez-A C, Marquez G, Goya I, Hamid Q, Fraser CC, Picarella D, Cote-Sierra J, Hodge MR, Gutierrez-Ramos JC, Kolbeck R, Coyle AJ. Gonzalo JA, et al. Among authors: kolbeck r. J Immunol. 2007 Aug 1;179(3):1740-50. doi: 10.4049/jimmunol.179.3.1740. J Immunol. 2007. PMID: 17641040
Expression of CCR8 is increased in asthma.
Mutalithas K, Guillen C, Raport C, Kolbeck R, Soler D, Brightling CE, Pavord ID, Wardlaw AJ. Mutalithas K, et al. Among authors: kolbeck r. Clin Exp Allergy. 2010 Aug;40(8):1175-85. doi: 10.1111/j.1365-2222.2010.03504.x. Epub 2010 Apr 28. Clin Exp Allergy. 2010. PMID: 20455898 Free PMC article.
143 results