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Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.
Yamanouchi J, Rainbow D, Serra P, Howlett S, Hunter K, Garner VE, Gonzalez-Munoz A, Clark J, Veijola R, Cubbon R, Chen SL, Rosa R, Cumiskey AM, Serreze DV, Gregory S, Rogers J, Lyons PA, Healy B, Smink LJ, Todd JA, Peterson LB, Wicker LS, Santamaria P. Yamanouchi J, et al. Among authors: veijola r. Nat Genet. 2007 Mar;39(3):329-37. doi: 10.1038/ng1958. Epub 2007 Feb 4. Nat Genet. 2007. PMID: 17277778 Free PMC article.
Linkage and association mapping of the LRP5 locus on chromosome 11q13 in type 1 diabetes.
Twells RC, Mein CA, Payne F, Veijola R, Gilbey M, Bright M, Timms A, Nakagawa Y, Snook H, Nutland S, Rance HE, Carr P, Dudbridge F, Cordell HJ, Cooper J, Tuomilehto-Wolf E, Tuomilehto J, Phillips M, Metzker M, Hess JF, Todd JA. Twells RC, et al. Among authors: veijola r. Hum Genet. 2003 Jul;113(2):99-105. doi: 10.1007/s00439-003-0940-6. Epub 2003 Apr 17. Hum Genet. 2003. PMID: 12700977
Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage.
Sioofy-Khojine AB, Richardson SJ, Locke JM, Oikarinen S, Nurminen N, Laine AP, Downes K, Lempainen J, Todd JA, Veijola R, Ilonen J, Knip M, Morgan NG, Hyöty H, Peakman M, Eichmann M. Sioofy-Khojine AB, et al. Among authors: veijola r. Diabetologia. 2022 Oct;65(10):1701-1709. doi: 10.1007/s00125-022-05753-y. Epub 2022 Jul 22. Diabetologia. 2022. PMID: 35867130 Free PMC article.
Haplotype structure, LD blocks, and uneven recombination within the LRP5 gene.
Twells RC, Mein CA, Phillips MS, Hess JF, Veijola R, Gilbey M, Bright M, Metzker M, Lie BA, Kingsnorth A, Gregory E, Nakagawa Y, Snook H, Wang WY, Masters J, Johnson G, Eaves I, Howson JM, Clayton D, Cordell HJ, Nutland S, Rance H, Carr P, Todd JA. Twells RC, et al. Among authors: veijola r. Genome Res. 2003 May;13(5):845-55. doi: 10.1101/gr.563703. Genome Res. 2003. PMID: 12727905 Free PMC article.
Th1/Th17 plasticity is a marker of advanced β cell autoimmunity and impaired glucose tolerance in humans.
Reinert-Hartwall L, Honkanen J, Salo HM, Nieminen JK, Luopajärvi K, Härkönen T, Veijola R, Simell O, Ilonen J, Peet A, Tillmann V, Knip M, Vaarala O; DIABIMMUNE Study Group; DIABIMMUNE Study Group. Reinert-Hartwall L, et al. Among authors: veijola r. J Immunol. 2015 Jan 1;194(1):68-75. doi: 10.4049/jimmunol.1401653. Epub 2014 Dec 5. J Immunol. 2015. PMID: 25480564 Free PMC article.
Circulating β cell-specific CD8+ T cells restricted by high-risk HLA class I molecules show antigen experience in children with and at risk of type 1 diabetes.
Yeo L, Pujol-Autonell I, Baptista R, Eichmann M, Kronenberg-Versteeg D, Heck S, Dolton G, Sewell AK, Härkönen T, Mikk ML, Toppari J, Veijola R, Knip M, Ilonen J, Peakman M. Yeo L, et al. Among authors: veijola r. Clin Exp Immunol. 2020 Mar;199(3):263-277. doi: 10.1111/cei.13391. Epub 2019 Nov 10. Clin Exp Immunol. 2020. PMID: 31660582 Free PMC article.
364 results