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Page 1
Discovery of tertiary aminoacids as dual PPARalpha/gamma agonists-I.
Devasthale PV, Chen S, Jeon Y, Qu F, Ryono DE, Wang W, Zhang H, Cheng L, Farrelly D, Golla R, Grover G, Ma Z, Moore L, Seethala R, Sun W, Doweyko AM, Chandrasena G, Sleph P, Hariharan N, Cheng PT. Devasthale PV, et al. Among authors: moore l. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2312-6. doi: 10.1016/j.bmcl.2007.01.060. Epub 2007 Jan 25. Bioorg Med Chem Lett. 2007. PMID: 17292606
Design and synthesis of N-[(4-methoxyphenoxy)carbonyl]-N-[[4-[2-(5- methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [Muraglitazar/BMS-298585], a novel peroxisome proliferator-activated receptor alpha/gamma dual agonist with efficacious glucose and lipid-lowering activities.
Devasthale PV, Chen S, Jeon Y, Qu F, Shao C, Wang W, Zhang H, Cap M, Farrelly D, Golla R, Grover G, Harrity T, Ma Z, Moore L, Ren J, Seethala R, Cheng L, Sleph P, Sun W, Tieman A, Wetterau JR, Doweyko A, Chandrasena G, Chang SY, Humphreys WG, Sasseville VG, Biller SA, Ryono DE, Selan F, Hariharan N, Cheng PT. Devasthale PV, et al. Among authors: moore l. J Med Chem. 2005 Mar 24;48(6):2248-50. doi: 10.1021/jm0496436. J Med Chem. 2005. PMID: 15771468
Design, synthesis and structure-activity relationships of azole acids as novel, potent dual PPAR alpha/gamma agonists.
Zhang H, Ryono DE, Devasthale P, Wang W, O'Malley K, Farrelly D, Gu L, Harrity T, Cap M, Chu C, Locke K, Zhang L, Lippy J, Kunselman L, Morgan N, Flynn N, Moore L, Hosagrahara V, Zhang L, Kadiyala P, Xu C, Doweyko AM, Bell A, Chang C, Muckelbauer J, Zahler R, Hariharan N, Cheng PT. Zhang H, et al. Among authors: moore l. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1451-6. doi: 10.1016/j.bmcl.2009.01.030. Epub 2009 Jan 15. Bioorg Med Chem Lett. 2009. PMID: 19201606
Chemical genetics reveals an RGS/G-protein role in the action of a compound.
Fitzgerald K, Tertyshnikova S, Moore L, Bjerke L, Burley B, Cao J, Carroll P, Choy R, Doberstein S, Dubaquie Y, Franke Y, Kopczynski J, Korswagen H, Krystek SR, Lodge NJ, Plasterk R, Starrett J, Stouch T, Thalody G, Wayne H, van der Linden A, Zhang Y, Walker SG, Cockett M, Wardwell-Swanson J, Ross-Macdonald P, Kindt RM. Fitzgerald K, et al. Among authors: moore l. PLoS Genet. 2006 Apr;2(4):e57. doi: 10.1371/journal.pgen.0020057. Epub 2006 Apr 21. PLoS Genet. 2006. PMID: 16683034 Free PMC article.
Therapeutic role of interferon-γ in experimental autoimmune encephalomyelitis is mediated through a tolerogenic subset of splenic CD11b+ myeloid cells.
Arellano G, Acuña E, Loda E, Moore L, Tichauer JE, Castillo C, Vergara F, Burgos PI, Penaloza-MacMaster P, Miller SD, Naves R. Arellano G, et al. Among authors: moore l. J Neuroinflammation. 2024 May 31;21(1):144. doi: 10.1186/s12974-024-03126-3. J Neuroinflammation. 2024. PMID: 38822334 Free PMC article.
The Management of Patients at High Risk of Serious COVID-19 Disease: Optimising the Patient Pathway in the Middle East, Africa, and Eastern Europe.
Al-Salman J, Amir A, Moore LS, Poulakou G, Soriano A, Abdallah J, Abutidze A, Amin W, El Assal G, Nombulelo M, Tarawneh F, Hassanien A. Al-Salman J, et al. Among authors: moore ls. Cureus. 2024 May 20;16(5):e60727. doi: 10.7759/cureus.60727. eCollection 2024 May. Cureus. 2024. PMID: 38779436 Free PMC article.
Infectious hepatitis E virus is associated with the mature sperm head.
Yadav KK, Boley PA, Laocharoensuk T, Khatiwada S, Lee CM, Bhandari M, Moore L, Hanson J, Kenney SP. Yadav KK, et al. Among authors: moore l. PLoS Pathog. 2024 May 20;20(5):e1012240. doi: 10.1371/journal.ppat.1012240. eCollection 2024 May. PLoS Pathog. 2024. PMID: 38768240 Free PMC article.
3,285 results