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Page 1
Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival.
Wiestner A, Tehrani M, Chiorazzi M, Wright G, Gibellini F, Nakayama K, Liu H, Rosenwald A, Muller-Hermelink HK, Ott G, Chan WC, Greiner TC, Weisenburger DD, Vose J, Armitage JO, Gascoyne RD, Connors JM, Campo E, Montserrat E, Bosch F, Smeland EB, Kvaloy S, Holte H, Delabie J, Fisher RI, Grogan TM, Miller TP, Wilson WH, Jaffe ES, Staudt LM. Wiestner A, et al. Among authors: gibellini f. Blood. 2007 Jun 1;109(11):4599-606. doi: 10.1182/blood-2006-08-039859. Epub 2007 Feb 13. Blood. 2007. PMID: 17299095 Free PMC article.
The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia.
Herishanu Y, Pérez-Galán P, Liu D, Biancotto A, Pittaluga S, Vire B, Gibellini F, Njuguna N, Lee E, Stennett L, Raghavachari N, Liu P, McCoy JP, Raffeld M, Stetler-Stevenson M, Yuan C, Sherry R, Arthur DC, Maric I, White T, Marti GE, Munson P, Wilson WH, Wiestner A. Herishanu Y, et al. Among authors: gibellini f. Blood. 2011 Jan 13;117(2):563-74. doi: 10.1182/blood-2010-05-284984. Epub 2010 Oct 12. Blood. 2011. PMID: 20940416 Free PMC article. Clinical Trial.
Activation of CD44, a receptor for extracellular matrix components, protects chronic lymphocytic leukemia cells from spontaneous and drug induced apoptosis through MCL-1.
Herishanu Y, Gibellini F, Njuguna N, Hazan-Halevy I, Farooqui M, Bern S, Keyvanfar K, Lee E, Wilson W, Wiestner A. Herishanu Y, et al. Among authors: gibellini f. Leuk Lymphoma. 2011 Sep;52(9):1758-69. doi: 10.3109/10428194.2011.569962. Epub 2011 Jun 8. Leuk Lymphoma. 2011. PMID: 21649540 Free PMC article.
Lenalidomide-induced upregulation of CD80 on tumor cells correlates with T-cell activation, the rapid onset of a cytokine release syndrome and leukemic cell clearance in chronic lymphocytic leukemia.
Aue G, Njuguna N, Tian X, Soto S, Hughes T, Vire B, Keyvanfar K, Gibellini F, Valdez J, Boss C, Samsel L, McCoy JP Jr, Wilson WH, Pittaluga S, Wiestner A. Aue G, et al. Among authors: gibellini f. Haematologica. 2009 Sep;94(9):1266-73. doi: 10.3324/haematol.2009.005835. Haematologica. 2009. PMID: 19734418 Free PMC article. Clinical Trial.
ON 01910.Na is selectively cytotoxic for chronic lymphocytic leukemia cells through a dual mechanism of action involving PI3K/AKT inhibition and induction of oxidative stress.
Chapman CM, Sun X, Roschewski M, Aue G, Farooqui M, Stennett L, Gibellini F, Arthur D, Pérez-Galán P, Wiestner A. Chapman CM, et al. Among authors: gibellini f. Clin Cancer Res. 2012 Apr 1;18(7):1979-91. doi: 10.1158/1078-0432.CCR-11-2113. Epub 2012 Feb 20. Clin Cancer Res. 2012. PMID: 22351695 Free PMC article.
Perforin gene mutations in patients with acquired aplastic anemia.
Solomou EE, Gibellini F, Stewart B, Malide D, Berg M, Visconte V, Green S, Childs R, Chanock SJ, Young NS. Solomou EE, et al. Among authors: gibellini f. Blood. 2007 Jun 15;109(12):5234-7. doi: 10.1182/blood-2006-12-063495. Epub 2007 Feb 20. Blood. 2007. PMID: 17311987 Free PMC article.
A clinical survey of mosaic single nucleotide variants in disease-causing genes detected by exome sequencing.
Cao Y, Tokita MJ, Chen ES, Ghosh R, Chen T, Feng Y, Gorman E, Gibellini F, Ward PA, Braxton A, Wang X, Meng L, Xiao R, Bi W, Xia F, Eng CM, Yang Y, Gambin T, Shaw C, Liu P, Stankiewicz P. Cao Y, et al. Among authors: gibellini f. Genome Med. 2019 Jul 26;11(1):48. doi: 10.1186/s13073-019-0658-2. Genome Med. 2019. PMID: 31349857 Free PMC article.
28 results