Bear JE - Search Results

1

Lack of extracellular signal-regulated kinase mitogen-activated protein kinase signaling shows a new type of melanoma.

Shields JM, Thomas NE, Cregger M, Berger AJ, Leslie M, Torrice C, Hao H, Penland S, Arbiser J, Scott G, Zhou T, Bar-Eli M, Bear JE, Der CJ, Kaufmann WK, Rimm DL, Sharpless NE. Shields JM, et al. Among authors: bear je. Cancer Res. 2007 Feb 15;67(4):1502-12. doi: 10.1158/0008-5472.CAN-06-3311. Cancer Res. 2007. PMID: 17308088

2

CD200 is induced by ERK and is a potential therapeutic target in melanoma.

Petermann KB, Rozenberg GI, Zedek D, Groben P, McKinnon K, Buehler C, Kim WY, Shields JM, Penland S, Bear JE, Thomas NE, Serody JS, Sharpless NE. Petermann KB, et al. Among authors: bear je. J Clin Invest. 2007 Dec;117(12):3922-9. doi: 10.1172/JCI32163. J Clin Invest. 2007. PMID: 18008004 Free PMC article.

3

Metastasis in an orthotopic murine model of melanoma is independent of RAS/RAF mutation.

Rozenberg GI, Monahan KB, Torrice C, Bear JE, Sharpless NE. Rozenberg GI, et al. Among authors: bear je. Melanoma Res. 2010 Oct;20(5):361-71. doi: 10.1097/CMR.0b013e328336ee17. Melanoma Res. 2010. PMID: 20679910 Free PMC article.

4

Arp2/3 is critical for lamellipodia and response to extracellular matrix cues but is dispensable for chemotaxis.

Wu C, Asokan SB, Berginski ME, Haynes EM, Sharpless NE, Griffith JD, Gomez SM, Bear JE. Wu C, et al. Among authors: bear je. Cell. 2012 Mar 2;148(5):973-87. doi: 10.1016/j.cell.2011.12.034. Cell. 2012. PMID: 22385962 Free PMC article.

5

LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanoma.

Liu W, Monahan KB, Pfefferle AD, Shimamura T, Sorrentino J, Chan KT, Roadcap DW, Ollila DW, Thomas NE, Castrillon DH, Miller CR, Perou CM, Wong KK, Bear JE, Sharpless NE. Liu W, et al. Among authors: bear je. Cancer Cell. 2012 Jun 12;21(6):751-64. doi: 10.1016/j.ccr.2012.03.048. Cancer Cell. 2012. PMID: 22698401 Free PMC article.

6

The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility.

Mitin N, Rossman KL, Currin R, Anne S, Marshall TW, Bear JE, Bautch VL, Der CJ. Mitin N, et al. Among authors: bear je. PLoS One. 2013 Jun 18;8(6):e66260. doi: 10.1371/journal.pone.0066260. Print 2013. PLoS One. 2013. PMID: 23825001 Free PMC article.

7

Loss of Arp2/3 induces an NF-κB-dependent, nonautonomous effect on chemotactic signaling.

Wu C, Haynes EM, Asokan SB, Simon JM, Sharpless NE, Baldwin AS, Davis IJ, Johnson GL, Bear JE. Wu C, et al. Among authors: bear je. J Cell Biol. 2013 Dec 23;203(6):907-16. doi: 10.1083/jcb.201306032. J Cell Biol. 2013. PMID: 24344184 Free PMC article.

8

LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues.

Chan KT, Asokan SB, King SJ, Bo T, Dubose ES, Liu W, Berginski ME, Simon JM, Davis IJ, Gomez SM, Sharpless NE, Bear JE. Chan KT, et al. Among authors: bear je. J Cell Biol. 2014 Oct 27;207(2):299-315. doi: 10.1083/jcb.201404067. J Cell Biol. 2014. PMID: 25349262 Free PMC article.

9

IL2 Inducible T-cell Kinase, a Novel Therapeutic Target in Melanoma.

Carson CC, Moschos SJ, Edmiston SN, Darr DB, Nikolaishvili-Feinberg N, Groben PA, Zhou X, Kuan PF, Pandey S, Chan KT, Jordan JL, Hao H, Frank JS, Hopkinson DA, Gibbs DC, Alldredge VD, Parrish E, Hanna SC, Berkowitz P, Rubenstein DS, Miller CR, Bear JE, Ollila DW, Sharpless NE, Conway K, Thomas NE. Carson CC, et al. Among authors: bear je. Clin Cancer Res. 2015 May 1;21(9):2167-76. doi: 10.1158/1078-0432.CCR-14-1826. Clin Cancer Res. 2015. PMID: 25934889 Free PMC article.

10

β2-adrenoceptor signaling regulates invadopodia formation to enhance tumor cell invasion.

Creed SJ, Le CP, Hassan M, Pon CK, Albold S, Chan KT, Berginski ME, Huang Z, Bear JE, Lane JR, Halls ML, Ferrari D, Nowell CJ, Sloan EK. Creed SJ, et al. Among authors: bear je. Breast Cancer Res. 2015 Nov 25;17(1):145. doi: 10.1186/s13058-015-0655-3. Breast Cancer Res. 2015. PMID: 26607426 Free PMC article.

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