Shields JM - Search Results

1

Lack of extracellular signal-regulated kinase mitogen-activated protein kinase signaling shows a new type of melanoma.

Shields JM, Thomas NE, Cregger M, Berger AJ, Leslie M, Torrice C, Hao H, Penland S, Arbiser J, Scott G, Zhou T, Bar-Eli M, Bear JE, Der CJ, Kaufmann WK, Rimm DL, Sharpless NE. Shields JM, et al. Cancer Res. 2007 Feb 15;67(4):1502-12. doi: 10.1158/0008-5472.CAN-06-3311. Cancer Res. 2007. PMID: 17308088

2

Opposing roles of the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in Ras-mediated downregulation of tropomyosin.

Shields JM, Mehta H, Pruitt K, Der CJ. Shields JM, et al. Mol Cell Biol. 2002 Apr;22(7):2304-17. doi: 10.1128/MCB.22.7.2304-2317.2002. Mol Cell Biol. 2002. PMID: 11884615 Free PMC article.

3

Defective cell cycle checkpoint functions in melanoma are associated with altered patterns of gene expression.

Kaufmann WK, Nevis KR, Qu P, Ibrahim JG, Zhou T, Zhou Y, Simpson DA, Helms-Deaton J, Cordeiro-Stone M, Moore DT, Thomas NE, Hao H, Liu Z, Shields JM, Scott GA, Sharpless NE. Kaufmann WK, et al. Among authors: shields jm. J Invest Dermatol. 2008 Jan;128(1):175-87. doi: 10.1038/sj.jid.5700935. Epub 2007 Jun 28. J Invest Dermatol. 2008. PMID: 17597816 Free PMC article.

4

Context-dependent roles of mutant B-Raf signaling in melanoma and colorectal carcinoma cell growth.

Hao H, Muniz-Medina VM, Mehta H, Thomas NE, Khazak V, Der CJ, Shields JM. Hao H, et al. Among authors: shields jm. Mol Cancer Ther. 2007 Aug;6(8):2220-9. doi: 10.1158/1535-7163.MCT-06-0728. Mol Cancer Ther. 2007. PMID: 17699719

5

CD200 is induced by ERK and is a potential therapeutic target in melanoma.

Petermann KB, Rozenberg GI, Zedek D, Groben P, McKinnon K, Buehler C, Kim WY, Shields JM, Penland S, Bear JE, Thomas NE, Serody JS, Sharpless NE. Petermann KB, et al. Among authors: shields jm. J Clin Invest. 2007 Dec;117(12):3922-9. doi: 10.1172/JCI32163. J Clin Invest. 2007. PMID: 18008004 Free PMC article.

6

Similar nucleotide excision repair capacity in melanocytes and melanoma cells.

Gaddameedhi S, Kemp MG, Reardon JT, Shields JM, Smith-Roe SL, Kaufmann WK, Sancar A. Gaddameedhi S, et al. Among authors: shields jm. Cancer Res. 2010 Jun 15;70(12):4922-30. doi: 10.1158/0008-5472.CAN-10-0095. Epub 2010 May 25. Cancer Res. 2010. PMID: 20501836 Free PMC article.

7

Loss of transgelin in breast and colon tumors and in RIE-1 cells by Ras deregulation of gene expression through Raf-independent pathways.

Shields JM, Rogers-Graham K, Der CJ. Shields JM, et al. J Biol Chem. 2002 Mar 22;277(12):9790-9. doi: 10.1074/jbc.M110086200. Epub 2001 Dec 28. J Biol Chem. 2002. PMID: 11773051 Free article.

8

Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling.

Huntington JT, Shields JM, Der CJ, Wyatt CA, Benbow U, Slingluff CL Jr, Brinckerhoff CE. Huntington JT, et al. Among authors: shields jm. J Biol Chem. 2004 Aug 6;279(32):33168-76. doi: 10.1074/jbc.M405102200. Epub 2004 Jun 7. J Biol Chem. 2004. PMID: 15184373 Free article.

9

Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells.

Pruitt K, Ulkü AS, Frantz K, Rojas RJ, Muniz-Medina VM, Rangnekar VM, Der CJ, Shields JM. Pruitt K, et al. Among authors: shields jm. J Biol Chem. 2005 Jun 17;280(24):23363-70. doi: 10.1074/jbc.M503083200. Epub 2005 Apr 14. J Biol Chem. 2005. PMID: 15831492 Free article.

10

Use of retrovirus expression of interfering RNA to determine the contribution of activated K-Ras and ras effector expression to human tumor cell growth.

Baines AT, Lim KH, Shields JM, Lambert JM, Counter CM, Der CJ, Cox AD. Baines AT, et al. Among authors: shields jm. Methods Enzymol. 2006;407:556-74. doi: 10.1016/S0076-6879(05)07045-X. Methods Enzymol. 2006. PMID: 16757353

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