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Analysis of genetic variation in Akt2/PKB-beta in severe insulin resistance, lipodystrophy, type 2 diabetes, and related metabolic phenotypes.
Diabetes. 2007 Mar;56(3):714-9. doi: 10.2337/db06-0921.
Diabetes. 2007.
PMID: 17327441
Free PMC article.
Functional characterization of naturally occurring pathogenic mutations in the human leptin receptor.
Kimber W, Peelman F, Prieur X, Wangensteen T, O'Rahilly S, Tavernier J, Farooqi IS.
Kimber W, et al.
Endocrinology. 2008 Dec;149(12):6043-52. doi: 10.1210/en.2008-0544. Epub 2008 Aug 14.
Endocrinology. 2008.
PMID: 18703626
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Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA.
López M, Lelliott CJ, Tovar S, Kimber W, Gallego R, Virtue S, Blount M, Vázquez MJ, Finer N, Powles TJ, O'Rahilly S, Saha AK, Diéguez C, Vidal-Puig AJ.
López M, et al.
Diabetes. 2006 May;55(5):1327-36. doi: 10.2337/db05-1356.
Diabetes. 2006.
PMID: 16644689
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Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor.
Farooqi IS, Wangensteen T, Collins S, Kimber W, Matarese G, Keogh JM, Lank E, Bottomley B, Lopez-Fernandez J, Ferraz-Amaro I, Dattani MT, Ercan O, Myhre AG, Retterstol L, Stanhope R, Edge JA, McKenzie S, Lessan N, Ghodsi M, De Rosa V, Perna F, Fontana S, Barroso I, Undlien DE, O'Rahilly S.
Farooqi IS, et al.
N Engl J Med. 2007 Jan 18;356(3):237-47. doi: 10.1056/NEJMoa063988.
N Engl J Med. 2007.
PMID: 17229951
Free PMC article.
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Dact1, a nutritionally regulated preadipocyte gene, controls adipogenesis by coordinating the Wnt/beta-catenin signaling network.
Lagathu C, Christodoulides C, Virtue S, Cawthorn WP, Franzin C, Kimber WA, Nora ED, Campbell M, Medina-Gomez G, Cheyette BN, Vidal-Puig AJ, Sethi JK.
Lagathu C, et al. Among authors: kimber wa.
Diabetes. 2009 Mar;58(3):609-19. doi: 10.2337/db08-1180. Epub 2008 Dec 10.
Diabetes. 2009.
PMID: 19073771
Free PMC article.
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Detection of novel intracellular agonist responsive pools of phosphatidylinositol 3,4-bisphosphate using the TAPP1 pleckstrin homology domain in immunoelectron microscopy.
Watt SA, Kimber WA, Fleming IN, Leslie NR, Downes CP, Lucocq JM.
Watt SA, et al. Among authors: kimber wa.
Biochem J. 2004 Feb 1;377(Pt 3):653-63. doi: 10.1042/BJ20031397.
Biochem J. 2004.
PMID: 14604433
Free PMC article.
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Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.
Kimber WA, Deak M, Prescott AR, Alessi DR.
Kimber WA, et al.
Biochem J. 2003 Dec 1;376(Pt 2):525-35. doi: 10.1042/BJ20031154.
Biochem J. 2003.
PMID: 14516276
Free PMC article.
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Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo.
Kimber WA, Trinkle-Mulcahy L, Cheung PC, Deak M, Marsden LJ, Kieloch A, Watt S, Javier RT, Gray A, Downes CP, Lucocq JM, Alessi DR.
Kimber WA, et al.
Biochem J. 2002 Feb 1;361(Pt 3):525-36. doi: 10.1042/0264-6021:3610525.
Biochem J. 2002.
PMID: 11802782
Free PMC article.
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