Gerhart-Hines Z - Search Results

1

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha.

Gerhart-Hines Z, Rodgers JT, Bare O, Lerin C, Kim SH, Mostoslavsky R, Alt FW, Wu Z, Puigserver P. Gerhart-Hines Z, et al. EMBO J. 2007 Apr 4;26(7):1913-23. doi: 10.1038/sj.emboj.7601633. Epub 2007 Mar 8. EMBO J. 2007. PMID: 17347648 Free PMC article.

2

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.

Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J. Lagouge M, et al. Cell. 2006 Dec 15;127(6):1109-22. doi: 10.1016/j.cell.2006.11.013. Epub 2006 Nov 16. Cell. 2006. PMID: 17112576 Free article.

3

Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways.

Rodgers JT, Lerin C, Gerhart-Hines Z, Puigserver P. Rodgers JT, et al. FEBS Lett. 2008 Jan 9;582(1):46-53. doi: 10.1016/j.febslet.2007.11.034. Epub 2007 Nov 26. FEBS Lett. 2008. PMID: 18036349 Free PMC article. Review.

4

Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells.

Suchankova G, Nelson LE, Gerhart-Hines Z, Kelly M, Gauthier MS, Saha AK, Ido Y, Puigserver P, Ruderman NB. Suchankova G, et al. Biochem Biophys Res Commun. 2009 Jan 23;378(4):836-41. doi: 10.1016/j.bbrc.2008.11.130. Epub 2008 Dec 9. Biochem Biophys Res Commun. 2009. PMID: 19071085 Free PMC article.

5

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity.

Cantó C, Gerhart-Hines Z, Feige JN, Lagouge M, Noriega L, Milne JC, Elliott PJ, Puigserver P, Auwerx J. Cantó C, et al. Nature. 2009 Apr 23;458(7241):1056-60. doi: 10.1038/nature07813. Nature. 2009. PMID: 19262508 Free PMC article.

6

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment.

Schafer ZT, Grassian AR, Song L, Jiang Z, Gerhart-Hines Z, Irie HY, Gao S, Puigserver P, Brugge JS. Schafer ZT, et al. Nature. 2009 Sep 3;461(7260):109-13. doi: 10.1038/nature08268. Epub 2009 Aug 19. Nature. 2009. PMID: 19693011 Free PMC article.

7

Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5.

Dominy JE Jr, Lee Y, Gerhart-Hines Z, Puigserver P. Dominy JE Jr, et al. Biochim Biophys Acta. 2010 Aug;1804(8):1676-83. doi: 10.1016/j.bbapap.2009.11.023. Epub 2009 Dec 11. Biochim Biophys Acta. 2010. PMID: 20005308 Free PMC article. Review.

8

The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+).

Gerhart-Hines Z, Dominy JE Jr, Blättler SM, Jedrychowski MP, Banks AS, Lim JH, Chim H, Gygi SP, Puigserver P. Gerhart-Hines Z, et al. Mol Cell. 2011 Dec 23;44(6):851-63. doi: 10.1016/j.molcel.2011.12.005. Mol Cell. 2011. PMID: 22195961 Free PMC article.

9

Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming.

Dominy JE, Gerhart-Hines Z, Puigserver P. Dominy JE, et al. Cold Spring Harb Symp Quant Biol. 2011;76:203-9. doi: 10.1101/sqb.2012.76.010843. Epub 2012 Feb 27. Cold Spring Harb Symp Quant Biol. 2011. PMID: 22371372 Review.

10

A metabolic prosurvival role for PML in breast cancer.

Carracedo A, Weiss D, Leliaert AK, Bhasin M, de Boer VC, Laurent G, Adams AC, Sundvall M, Song SJ, Ito K, Finley LS, Egia A, Libermann T, Gerhart-Hines Z, Puigserver P, Haigis MC, Maratos-Flier E, Richardson AL, Schafer ZT, Pandolfi PP. Carracedo A, et al. J Clin Invest. 2012 Sep;122(9):3088-100. doi: 10.1172/JCI62129. Epub 2012 Aug 13. J Clin Invest. 2012. PMID: 22886304 Free PMC article.

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