Hakkarainen T - Search Results

1

Luciferase imaging for evaluation of oncolytic adenovirus replication in vivo.

Guse K, Dias JD, Bauerschmitz GJ, Hakkarainen T, Aavik E, Ranki T, Pisto T, Särkioja M, Desmond RA, Kanerva A, Hemminki A. Guse K, et al. Among authors: hakkarainen t. Gene Ther. 2007 Jun;14(11):902-11. doi: 10.1038/sj.gt.3302949. Epub 2007 Mar 22. Gene Ther. 2007. PMID: 17377596

2

Noninvasive dual modality in vivo monitoring of the persistence and potency of a tumor targeted conditionally replicating adenovirus.

Kanerva A, Zinn KR, Peng KW, Ranki T, Kangasniemi L, Chaudhuri TR, Desmond RA, Wang M, Takayama K, Hakkarainen T, Alfthan H, Stenman UH, Curiel DT, Hemminki A. Kanerva A, et al. Among authors: hakkarainen t. Gene Ther. 2005 Jan;12(1):87-94. doi: 10.1038/sj.gt.3302387. Gene Ther. 2005. PMID: 15385953

3

A heparan sulfate-targeted conditionally replicative adenovirus, Ad5.pk7-Delta24, for the treatment of advanced breast cancer.

Ranki T, Kanerva A, Ristimäki A, Hakkarainen T, Särkioja M, Kangasniemi L, Raki M, Laakkonen P, Goodison S, Hemminki A. Ranki T, et al. Among authors: hakkarainen t. Gene Ther. 2007 Jan;14(1):58-67. doi: 10.1038/sj.gt.3302830. Epub 2006 Aug 10. Gene Ther. 2007. PMID: 16900223 Free PMC article.

4

Utility of TK/GCV in the context of highly effective oncolysis mediated by a serotype 3 receptor targeted oncolytic adenovirus.

Raki M, Hakkarainen T, Bauerschmitz GJ, Särkioja M, Desmond RA, Kanerva A, Hemminki A. Raki M, et al. Among authors: hakkarainen t. Gene Ther. 2007 Oct;14(19):1380-8. doi: 10.1038/sj.gt.3302992. Epub 2007 Jul 5. Gene Ther. 2007. PMID: 17611584

5

Changing the adenovirus fiber for retaining gene delivery efficacy in the presence of neutralizing antibodies.

Särkioja M, Pesonen S, Raki M, Hakkarainen T, Salo J, Ahonen MT, Kanerva A, Hemminki A. Särkioja M, et al. Among authors: hakkarainen t. Gene Ther. 2008 Jun;15(12):921-9. doi: 10.1038/gt.2008.56. Epub 2008 Apr 10. Gene Ther. 2008. PMID: 18401431

6

Extended release of adenovirus from silica implants in vitro and in vivo.

Kangasniemi L, Koskinen M, Jokinen M, Toriseva M, Ala-Aho R, Kähäri VM, Jalonen H, Ylä-Herttuala S, Moilanen H, Stenman UH, Diaconu I, Kanerva A, Pesonen S, Hakkarainen T, Hemminki A. Kangasniemi L, et al. Among authors: hakkarainen t. Gene Ther. 2009 Jan;16(1):103-10. doi: 10.1038/gt.2008.142. Epub 2008 Aug 28. Gene Ther. 2009. PMID: 18754041

7

Ad5/3-9HIF-Delta24-VEGFR-1-Ig, an infectivity enhanced, dual-targeted and antiangiogenic oncolytic adenovirus for kidney cancer treatment.

Guse K, Diaconu I, Rajecki M, Sloniecka M, Hakkarainen T, Ristimäki A, Kanerva A, Pesonen S, Hemminki A. Guse K, et al. Among authors: hakkarainen t. Gene Ther. 2009 Aug;16(8):1009-20. doi: 10.1038/gt.2009.56. Epub 2009 May 14. Gene Ther. 2009. PMID: 19440223

8

Production of an EGFR targeting molecule from a conditionally replicating adenovirus impairs its oncolytic potential.

Hemminki A, Wang M, Hakkarainen T, Desmond RA, Wahlfors J, Curiel DT. Hemminki A, et al. Among authors: hakkarainen t. Cancer Gene Ther. 2003 Aug;10(8):583-8. doi: 10.1038/sj.cgt.7700606. Cancer Gene Ther. 2003. PMID: 12872139

9

Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus.

Kanerva A, Zinn KR, Chaudhuri TR, Lam JT, Suzuki K, Uil TG, Hakkarainen T, Bauerschmitz GJ, Wang M, Liu B, Cao Z, Alvarez RD, Curiel DT, Hemminki A. Kanerva A, et al. Among authors: hakkarainen t. Mol Ther. 2003 Sep;8(3):449-58. doi: 10.1016/s1525-0016(03)00200-4. Mol Ther. 2003. PMID: 12946318 Free article.

10

Triple-targeted oncolytic adenoviruses featuring the cox2 promoter, E1A transcomplementation, and serotype chimerism for enhanced selectivity for ovarian cancer cells.

Bauerschmitz GJ, Guse K, Kanerva A, Menzel A, Herrmann I, Desmond RA, Yamamoto M, Nettelbeck DM, Hakkarainen T, Dall P, Curiel DT, Hemminki A. Bauerschmitz GJ, et al. Among authors: hakkarainen t. Mol Ther. 2006 Aug;14(2):164-74. doi: 10.1016/j.ymthe.2006.01.010. Epub 2006 Mar 31. Mol Ther. 2006. PMID: 16580264 Free article.

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