Särkioja M - Search Results

1

Luciferase imaging for evaluation of oncolytic adenovirus replication in vivo.

Guse K, Dias JD, Bauerschmitz GJ, Hakkarainen T, Aavik E, Ranki T, Pisto T, Särkioja M, Desmond RA, Kanerva A, Hemminki A. Guse K, et al. Among authors: sarkioja m. Gene Ther. 2007 Jun;14(11):902-11. doi: 10.1038/sj.gt.3302949. Epub 2007 Mar 22. Gene Ther. 2007. PMID: 17377596

2

Noninvasive imaging for evaluation of the systemic delivery of capsid-modified adenoviruses in an orthotopic model of advanced lung cancer.

Sarkioja M, Kanerva A, Salo J, Kangasniemi L, Eriksson M, Raki M, Ranki T, Hakkarainen T, Hemminki A. Sarkioja M, et al. Cancer. 2006 Oct 1;107(7):1578-88. doi: 10.1002/cncr.22209. Cancer. 2006. PMID: 16948124 Free article.

3

Chlorpromazine and apigenin reduce adenovirus replication and decrease replication associated toxicity.

Kanerva A, Raki M, Ranki T, Särkioja M, Koponen J, Desmond RA, Helin A, Stenman UH, Isoniemi H, Höckerstedt K, Ristimäki A, Hemminki A. Kanerva A, et al. Among authors: sarkioja m. J Gene Med. 2007 Jan;9(1):3-9. doi: 10.1002/jgm.984. J Gene Med. 2007. PMID: 17149790

4

Treatment of prostate cancer with Ad5/3Delta24hCG allows non-invasive detection of the magnitude and persistence of virus replication in vivo.

Rajecki M, Kanerva A, Stenman UH, Tenhunen M, Kangasniemi L, Särkioja M, Ala-Opas MY, Alfthan H, Sankila A, Rintala E, Desmond RA, Hakkarainen T, Hemminki A. Rajecki M, et al. Among authors: sarkioja m. Mol Cancer Ther. 2007 Feb;6(2):742-51. doi: 10.1158/1535-7163.MCT-06-0403. Mol Cancer Ther. 2007. PMID: 17308070

5

Systemic efficacy of oncolytic adenoviruses in imagable orthotopic models of hormone refractory metastatic breast cancer.

Ranki T, Särkioja M, Hakkarainen T, von Smitten K, Kanerva A, Hemminki A. Ranki T, et al. Among authors: sarkioja m. Int J Cancer. 2007 Jul 1;121(1):165-74. doi: 10.1002/ijc.22627. Int J Cancer. 2007. PMID: 17315187 Free article.

6

Human mesenchymal stem cells lack tumor tropism but enhance the antitumor activity of oncolytic adenoviruses in orthotopic lung and breast tumors.

Hakkarainen T, Särkioja M, Lehenkari P, Miettinen S, Ylikomi T, Suuronen R, Desmond RA, Kanerva A, Hemminki A. Hakkarainen T, et al. Among authors: sarkioja m. Hum Gene Ther. 2007 Jul;18(7):627-41. doi: 10.1089/hum.2007.034. Hum Gene Ther. 2007. PMID: 17604566

7

Treatment of metastatic renal cancer with capsid-modified oncolytic adenoviruses.

Guse K, Ranki T, Ala-Opas M, Bono P, Särkioja M, Rajecki M, Kanerva A, Hakkarainen T, Hemminki A. Guse K, et al. Among authors: sarkioja m. Mol Cancer Ther. 2007 Oct;6(10):2728-36. doi: 10.1158/1535-7163.MCT-07-0176. Mol Cancer Ther. 2007. PMID: 17938266

8

Oncolytic adenovirus Ad5/3-delta24 and chemotherapy for treatment of orthotopic ovarian cancer.

Raki M, Särkioja M, Desmond RA, Chen DT, Bützow R, Hemminki A, Kanerva A. Raki M, et al. Among authors: sarkioja m. Gynecol Oncol. 2008 Jan;108(1):166-72. doi: 10.1016/j.ygyno.2007.09.013. Epub 2007 Oct 22. Gynecol Oncol. 2008. PMID: 17950450

9

The cyclo-oxygenase 2 promoter is induced in nontarget cells following adenovirus infection, but an AU-rich 3'-untranslated region destabilization element can increase specificity.

Särkioja M, Hakkarainen T, Eriksson M, Ristimäki A, Desmond RA, Kanerva A, Hemminki A. Särkioja M, et al. J Gene Med. 2008 Jul;10(7):744-53. doi: 10.1002/jgm.1193. J Gene Med. 2008. PMID: 18338835

10

Combination of gemcitabine and Ad5/3-Delta24, a tropism modified conditionally replicating adenovirus, for the treatment of ovarian cancer.

Raki M, Kanerva A, Ristimaki A, Desmond RA, Chen DT, Ranki T, Sarkioja M, Kangasniemi L, Hemminki A. Raki M, et al. Among authors: sarkioja m. Gene Ther. 2005 Aug;12(15):1198-205. doi: 10.1038/sj.gt.3302517. Gene Ther. 2005. PMID: 15800658

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